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Sleep-Ease CR

product on market Tablet or Pill Woodstock Vitamins Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 100% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · grounded in 1 source · methodology

Melatonin and Vitamin B6 are utilized to support sleep onset and regulate circadian rhythms. There is strong evidence for melatonin's efficacy in reducing sleep latency, while B6 plays a supporting role in neurotransmitter synthesis. Evidence coverage for this specific formulation is limited.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for Sleep-Ease CR
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Tablet(s)
Serving Size
90
Servings
Other Combinations
Product Type
100%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

10 mg (588% DV)
7.7× RDA — above typical dose (UL: 100 mg) 114 studies (A:3, B:35)
5 mg
Market median: 3.0mg (984 products) 240 studies (A:2, B:109)

Other Ingredients

Cellulose Dibasic Calcium Phosphate Hypromellose Magnesium Stearate Stearic Acid Silica Methylcellulose Glycerin
Claims

Label Claims — Verification

Unverified All Other
Info

Product Information

Directions for Use

Directions: Take one tablet with water 20 minutes before bedtime, or as directed by your healthcare practitioner.

Warnings & Precautions

Consult your healthcare practitioner prior to use.

Individuals taking medication should discuss potential interactions with their healthcare practitioner.

Do not use if tamper seal is damaged.

Cautions: Not for use by children under 12 years of age.

Do not take when operating machinery or driving a vehicle.

Storage: Keep closed in a cool, dry place out of reach of children.

Formulation Notes

Sleep-Ease CR is a vegetarian formula with a biphasic delivery system that releases melatonin quickly and then steadily.

Melatonin is naturally produced in the pineal gland in response to changes in light exposure; it helps promote healthy sleep patterns as well as antioxidant and immune activities.

Sleep-Ease CR can support these functions by helping to maintain normal levels of melatonin in the body.

Does not contain: Wheat, gluten, corn, yeast, soy, animal or dairy products, fish, shellfish, peanuts, tree nuts, egg, artificial colors, artificial sweeteners, or preservatives.

Biphasic controlled-release melatonin formula

Manufactured in a GMP compliant facility.

Additional Information

Storage: Keep closed in a cool, dry place out of reach of children.

Professional use only This package is completely recyclable

Metadata

Product Details

UPC / SKU6 69439 84318 5
DSLD Entry Date2020-03-24
Product TypeOther Combinations
FormTablet or Pill
BrandWoodstock Vitamins
DSLD ID216703
Data Updated2026-04-11
Research

Research Evidence

153
Research Sources
55
Avg Quality
71
Systematic Review
51
Meta Analysis
19
Rct
6
Clinical Trial
2
Other
2
Regulatory Source
1
Openfda Safety
A Efficacy of vitamin and antioxidant supplements in prevention of cardiovascular disease: systematic review and meta-analysis of randomised controlled trials
Meta Analysis BMJ (Clinical research ed.) 2013 PubMed DOI
A Homocysteine lowering interventions for preventing cardiovascular events
Meta Analysis The Cochrane database of systematic reviews 2009 PubMed DOI
A Intake of vitamin B6, folate, and vitamin B12 and risk of coronary heart disease: a systematic review and dose-response meta-analysis of prospective cohort studies
Meta Analysis Critical reviews in food science and nutrition 2019 PubMed DOI
A Exploring the causal associations of micronutrients on urate levels and the risk of gout: A Mendelian randomization study
Meta Analysis Clinical nutrition (Edinburgh, Scotland) 2024 PubMed DOI
A Pyridoxine (vitamin B6) supplementation during pregnancy or labour for maternal and neonatal outcomes
Meta Analysis The Cochrane database of systematic reviews 2015 PubMed DOI
B Prophylactic drug management for febrile seizures in children
Meta Analysis The Cochrane database of systematic reviews 2021 PubMed DOI
B Treatments for Hyperemesis Gravidarum and Nausea and Vomiting in Pregnancy: A Systematic Review
Systematic Review JAMA 2016 PubMed DOI
B The potential role of nutritional components in improving brain function among patients with Alzheimers disease: a meta-analysis of RCT studies
Meta Analysis Neurosciences (Riyadh, Saudi Arabia) 2020 PubMed DOI
B Pyridoxine (vitamin B6) supplementation in pregnancy
Meta Analysis The Cochrane database of systematic reviews 2006 PubMed
B Effect of ginger in the treatment of nausea and vomiting compared with vitamin B6 and placebo during pregnancy: a meta-analysis
Meta Analysis The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians 2022 PubMed DOI
View all evidence for Vitamin B6 →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.