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Magnesium 500 mg

product on market Tablet or Pill Major Safety: 60/100
60/100

Review before taking

  • Magnesium: 500mg is 1.4× the Tolerable Upper Intake Level (350mg)
  • 100% of ingredients have research evidence
C Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · grounded in 1 source · methodology

Magnesium supports muscle and nerve function, with strong evidence for its role in metabolic health. However, the limited evidence coverage for this specific formulation and a safety score of 60 suggest potential concerns. Users should be aware of possible adverse effects or contraindications.

AI-generated summary based on research evidence. Not medical advice.

Alerts

Safety Alerts

Magnesium: 500mg is 1.4× the Tolerable Upper Intake Level (350mg)

AI-generated · Qwen 3.6 · grounded in 2 sources · methodology

This product received a low safety score because the amount of magnesium exceeds the recommended daily upper limit. Specifically, it provides 1.4 times the maximum suggested intake level.

Label

Product Label

Label for Magnesium 500 mg
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Tablet(s)
Serving Size
Mineral
Product Type
100%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

500 mg (119% DV)
Exceeds UL by 1.4× (UL: 350 mg) 316 studies (A:8, B:159)

Other Ingredients

Microcrystalline Cellulose Dicalcium Phosphate Croscarmellose Sodium Magnesium Stearate Hypromellose Titanium Dioxide Polyethylene Glycol Poloxamer Talc Triacetin Crospovidone Stearic Acid Mineral Oil Sodium Lauryl Sulfate
Claims

Label Claims — Verification

Unverified Nutrient
Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Directions: For adults, take one (1) tablet daily, preferably with a meal. As a reminder, discuss the supplements and medications you take with your health care provider.

Warnings & Precautions

Warning: If you are pregnant, nursing or taking any medications, or have any medical condition, consult your doctor before use.

Discontinue use and consult your doctor if any adverse reactions occur.

Keep out of the reach of children.

Tamper Resistant: Do not use if seal under cap is broken or missing.

Formulation Notes

Potency guaranteed

Plays a role in maintaining optimal bone health

Free of: Yeast, wheat, gluten, milk or milk derivatives, lactose, sugar, preservatives, soy, artificial flavor, sodium (less than 5 mg per serving).

Magnesium plays an essential role in maintaining proper bone mineralization. Magnesium is involved in muscle contractions and nerve impulses.

Tablets meet USP disintegration test.

Additional Information

New formula

Store at room temperature and avoid excessive heat.

Metadata

Product Details

UPC / SKU3 09044 23960 6
DSLD Entry Date2020-03-24
Product TypeMineral
FormTablet or Pill
BrandMajor
DSLD ID215959
Data Updated2026-04-11
Research

Research Evidence

849
Research Sources
56
Avg Quality
450
Meta Analysis
152
Rct
137
Systematic Review
73
Clinical Trial
11
Regulatory Source
7
Other
7
Guideline
3
Openfda Safety
2
Cochrane Review
2
Observational
A Phosphate binders for preventing and treating chronic kidney disease-mineral and bone disorder (CKD-MBD)
Meta Analysis The Cochrane database of systematic reviews 2018 PubMed DOI
A Calcium supplementation (other than for preventing or treating hypertension) for improving pregnancy and infant outcomes
Meta Analysis The Cochrane database of systematic reviews 2024 PubMed DOI
A Calcium supplementation (other than for preventing or treating hypertension) for improving pregnancy and infant outcomes
Meta Analysis The Cochrane database of systematic reviews 2015 PubMed DOI
A Vitamin and mineral supplementation for maintaining cognitive function in cognitively healthy people in mid and late life
Meta Analysis The Cochrane database of systematic reviews 2018 PubMed DOI
A Calcium supplementation during pregnancy for preventing hypertensive disorders and related problems
Meta Analysis The Cochrane database of systematic reviews 2025 PubMed DOI
A Dietary calcium supplementation for preventing colorectal cancer and adenomatous polyps
Systematic Review The Cochrane database of systematic reviews 2008 PubMed DOI
A Calcium and vitamin D for increasing bone mineral density in premenopausal women
Systematic Review The Cochrane database of systematic reviews 2023 PubMed DOI
A Dietary sodium, sodium-to-potassium ratio, and risk of stroke: A systematic review and nonlinear dose-response meta-analysis
Meta Analysis Clinical nutrition (Edinburgh, Scotland) 2019 PubMed DOI
A The association between circulating magnesium and clinically relevant outcomes in patients with chronic kidney disease: A systematic review and meta-analysis
Meta Analysis Clinical nutrition (Edinburgh, Scotland) 2021 PubMed DOI
A Calcium channel blockers versus other classes of drugs for hypertension
Systematic Review The Cochrane database of systematic reviews 2021 PubMed DOI
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.