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Milk Thistle Supreme

product on market Capsule PureFormulas Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 100% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · grounded in 1 source · methodology

Milk thistle extract contains silymarin, which is researched for its potential to support liver function and protect hepatocytes. However, the overall evidence coverage for this specific profile is very limited. Clinical data on its efficacy remains mixed across various liver conditions.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for Milk Thistle Supreme
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Vegetarian Capsule(s)
Serving Size
60
Servings
Other Combinations
Product Type
100%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Market median: 250.0mg (562 products) 55 studies (A:0, B:19)
100 mg
Market median: 250.0mg (562 products) 55 studies (A:0, B:19)

Other Ingredients

Cellulose Hydroxypropyl Methylcellulose Vegetable Stearate
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Suggested usage: As a dietary supplement, adults take 1 capsule twice daily between meals, or as advised by your healthcare professional. If digestive irritation occurs, take with meals.

Warnings & Precautions

Stop use and consult your healthcare professional if allergic reactions occur.

Note: If you are pregnant or nursing consult your healthcare professional before using this product.

Keep out of reach of children.

Tamper resistant package, do not use if outer seal is missing.

Formulation Notes

Milk thistle (Silybum marianum (L.) Gaertn.) has been in common medicinal use since the middle ages in Europe. Silymarin is a combination of three potent flavonoids (silybin, silydianin and silychristin). This extract is standardized to 80% silymarin flavonoids.

This product contains no yeast, wheat, gluten, soy, milk/dairy, corn, sugar, starch, artificial preservatives, artificial flavoring. or genetically modified organisms (GMOs).

Additional Information

For optimal storage conditions, store in a cool, dry place. (59(0)-77(0)F/15(0)-25(0)C) (35-65% relative humidity)

Live life pure.

Liver support

Non-GMO

Metadata

Product Details

UPC / SKUPUF1085
DSLD Entry Date2019-08-23
Product TypeOther Combinations
FormCapsule
BrandPureFormulas
DSLD ID205765
Data Updated2026-04-11
Research

Research Evidence

69
Research Sources
55
Avg Quality
34
Meta Analysis
26
Systematic Review
5
Rct
3
Clinical Trial
1
Openfda Safety
A Silymarin for adults with metabolic dysfunction-associated steatotic liver disease
Meta Analysis The Cochrane database of systematic reviews 2025 PubMed DOI
B Evaluation of the effect of herbal agents as management of radiodermatitis in breast cancer patients: A systematic review and meta-analysis
Meta Analysis Japan journal of nursing science : JJNS 2024 PubMed DOI
B Efficacy of different interventions for nonalcoholic fatty liver disease: A meta-analysis of lifestyle modifications, silymarin, and medications
Meta Analysis Asia Pacific journal of clinical nutrition 2025 PubMed DOI
B Milk thistle for alcoholic and/or hepatitis B or C virus liver diseases
Meta Analysis The Cochrane database of systematic reviews 2007 PubMed
B Pharmacotherapy for trichotillomania
Meta Analysis The Cochrane database of systematic reviews 2021 PubMed DOI
B Effects berberine-silymarin on liver enzymes: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Clinical nutrition ESPEN 2022 PubMed DOI
B Efficacy of traditional Chinese medicine combined with Silibinin on nonalcoholic fatty liver disease: A meta-analysis and systematic review
Meta Analysis Medicine 2024 PubMed DOI
B Are alterations needed in Silybum marianum (Silymarin) administration practices? A novel outlook and meta-analysis on randomized trials targeting liver injury
Meta Analysis BMC complementary medicine and therapies 2025 PubMed DOI
B The therapeutic effects of silymarin for patients with glucose/lipid metabolic dysfunction: A meta-analysis
Meta Analysis Medicine 2020 PubMed DOI
B Administration of silymarin in NAFLD/NASH: A systematic review and meta-analysis
Meta Analysis Annals of hepatology 2024 PubMed DOI
View all evidence for Milk Thistle →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.