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Milk Thistle Extract

product on market Capsule 21st Century Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 100% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · grounded in 1 source · methodology

Milk thistle extract contains silymarin, which is researched for its potential to support liver function and protect hepatic cells from toxins. Evidence for these effects is generally considered moderate, though results vary across clinical studies. This ingredient profile maintains a high safety rating for most healthy adults.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for Milk Thistle Extract
Open Full PDF View on NIH DSLD →
Details

Label Data

2 Vegetarian Capsule(s)
Serving Size
30
Servings
Botanical
Product Type
100%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Market median: 250.0mg (562 products) 55 studies (A:0, B:19)

Other Ingredients

Cellulose Starch Contains Less Than 2% of
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Directions: As a herbal supplement, adults take two (2) capsules daily with any meal or as directed by a healthcare provider. Do not exceed recommended dosage.

Warnings & Precautions

Do not exceed recommended dosage.

Warning: Consult a healthcare provider prior to use if pregnant, nursing, on medications, have a medical condition or are planning a medical procedure.

Stop use and contact a physician if adverse reactions occur.

Keep out of reach of children.

Do not use if product appears to be tampered with or seal is broken.

Formulation Notes

No added Sugar, Salt, Yeast, Preservatives, Artificial Flavors or Colors.

100% Vegetarian.

Gluten free

Milk Thistle Extract has been traditionally used to support liver health. Silymarin, the active complex found in Milk Thistle Extract, supports antioxidant activity.

Additional Information

Individual results may vary.

Store at room temperature.

Standardized Healthy Liver Support

Gluten free

Guaranteed quality Laboratory tested

Metadata

Product Details

UPC / SKU7 40985 21338 4
DSLD Entry Date2019-08-23
Product TypeBotanical
FormCapsule
DSLD ID205614
Data Updated2026-04-11
Research

Research Evidence

69
Research Sources
55
Avg Quality
34
Meta Analysis
26
Systematic Review
5
Rct
3
Clinical Trial
1
Openfda Safety
A Silymarin for adults with metabolic dysfunction-associated steatotic liver disease
Meta Analysis The Cochrane database of systematic reviews 2025 PubMed DOI
B Evaluation of the effect of herbal agents as management of radiodermatitis in breast cancer patients: A systematic review and meta-analysis
Meta Analysis Japan journal of nursing science : JJNS 2024 PubMed DOI
B Efficacy of different interventions for nonalcoholic fatty liver disease: A meta-analysis of lifestyle modifications, silymarin, and medications
Meta Analysis Asia Pacific journal of clinical nutrition 2025 PubMed DOI
B Milk thistle for alcoholic and/or hepatitis B or C virus liver diseases
Meta Analysis The Cochrane database of systematic reviews 2007 PubMed
B Pharmacotherapy for trichotillomania
Meta Analysis The Cochrane database of systematic reviews 2021 PubMed DOI
B Effects berberine-silymarin on liver enzymes: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Clinical nutrition ESPEN 2022 PubMed DOI
B Efficacy of traditional Chinese medicine combined with Silibinin on nonalcoholic fatty liver disease: A meta-analysis and systematic review
Meta Analysis Medicine 2024 PubMed DOI
B Are alterations needed in Silybum marianum (Silymarin) administration practices? A novel outlook and meta-analysis on randomized trials targeting liver injury
Meta Analysis BMC complementary medicine and therapies 2025 PubMed DOI
B The therapeutic effects of silymarin for patients with glucose/lipid metabolic dysfunction: A meta-analysis
Meta Analysis Medicine 2020 PubMed DOI
B Administration of silymarin in NAFLD/NASH: A systematic review and meta-analysis
Meta Analysis Annals of hepatology 2024 PubMed DOI
View all evidence for Milk Thistle →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.