100/100
This product looks safe
- No ingredients exceed tolerable upper intake levels
- 100% of ingredients have research evidence
A
Label Compliance Grade
What the Evidence Says
✨ AI-generated · Qwen 3.6 · grounded in 1 source
· methodology
5-HTP serves as a precursor to serotonin and is used in research to support mood and sleep regulation. There is moderate evidence suggesting its effectiveness for managing depressive symptoms, though clinical data is limited. The ingredient is generally well-tolerated when used as directed.
AI-generated summary based on research evidence. Not medical advice.
Details
Label Data
1 Lozenge(s)
Serving Size
Amino acid/Protein
Product Type
Ingredients
Supplement Facts — Evidence Check
Market median: 100.0mg (116 products)
18 studies (A:0, B:3)
Other Ingredients
Lactose
Stearic Acid
Croscarmelose Sodium
Magnesium Stearate
Silicon Dioxide
Claims
Label Claims — Verification
Info
Product Information
Directions for Use
For best results avoid taking Vitamin B6 two (2) hours before or after taking 5-HTP.
Suggested Use: Doses vary according to use. Consult your health care professional.
Warnings & Precautions
For best results avoid taking Vitamin B6 two (2) hours before or after taking 5-HTP.
Formulation Notes
5-Hydroxy-L-Tryptophan 25
Additional Information
5-HTP (5-hydroxy-L-tryptophan) is the immediate precursor of serotonin. Low levels of serotonin are associated with depression, obesity and sleep disorders.
Metadata
Product Details
UPC / SKU6 39793 10106 1
DSLD Entry Date2012-08-24
Product TypeAmino acid/Protein
FormUnknown
Data Updated2026-04-11
Research
Research Evidence
B
Combination pharmacotherapy for the treatment of fibromyalgia in adults
Systematic Review
The Cochrane database of systematic reviews
2018
PubMed
DOI
B
Tryptophan and 5-hydroxytryptophan for depression
Systematic Review
The Cochrane database of systematic reviews
2001
PubMed
B
Tryptophan and 5-hydroxytryptophan for depression
Systematic Review
The Cochrane database of systematic reviews
2002
PubMed
B
The impact of 5-hydroxytryptophan supplementation on sleep quality and gut microbiota composition in older adults: A randomized controlled trial
Rct
Clinical nutrition (Edinburgh, Scotland)
2024
PubMed
DOI
B
The Impact of 5-Hydroxytryptophan Supplementation on Cognitive Function and Mood in Singapore Older Adults: A Randomized Controlled Trial
B
The Efficacy of Different Triptans for the Treatment of Acute Headache in Pediatric Migraine: A Systematic Review
Systematic Review
Indian pediatrics
2023
PubMed
B
The effect of therapeutic massage combined with conventional therapy in children with functional dyspepsia: a systematic review and meta-analysis
Systematic Review
Frontiers in pharmacology
2025
PubMed
DOI
C
Sleep disorders in children
Systematic Review
BMJ clinical evidence
2010
PubMed
C
Effects of 5-hydroxytryptophan on distinct types of depression: a systematic review and meta-analysis
Meta Analysis
Nutrition reviews
2020
PubMed
DOI
C
Investigating genetic links between biological aging and adverse pregnancy outcomes
View all evidence for 5 Htp →
This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.
