Standardized senna in the management of constipation in the puerperium: A clinical trial

Shelton et al., 1980 | S Afr Med J | Rct

Citation

Shelton M G. Standardized senna in the management of constipation in the puerperium: A clinical trial. S Afr Med J. 1980-Jan-19;57(3):78-80

Abstract

Successful treatment of constipation in the immediate postpartum period in 93% of White patients and 96% of Coloured patients was achieved in a clinical trial of standardized senna tablets (Senokot; Reckitt & Colman). This is significantly better than the success rates of 51% and 59% achieved in White and Coloured controls treated with a placebo. Minor abdominal cramps occurred in some 13% of the patients treated with standardized senna, and in 4% of the controls given the placebo. There is no evidence to suggest that standardized senna has any effect whatsoever on a breast-fed baby if taken by the mother.

Key Findings

There is no evidence to suggest that standardized senna has any effect whatsoever on a breast-fed baby if taken by the mother.

Outcomes Measured

  • Requires manual extraction

Population

Field Value
Population See abstract
Sample Size See abstract
Age Range See abstract
Condition See abstract

MeSH Terms

  • Adult
  • Breast Feeding
  • Clinical Trials as Topic
  • Constipation
  • Diarrhea, Infantile
  • Double-Blind Method
  • Female
  • Humans
  • Pregnancy
  • Puerperal Disorders
  • Senna Extract

Evidence Classification

  • Level: Rct
  • Publication Types: Clinical Trial, Controlled Clinical Trial, Journal Article, Randomized Controlled Trial
  • Vertical: senna

Provenance

  • PMID: 6996138
  • DOI: (not available)
  • PMCID: Not in PMC
  • Verified: 2026-04-12 via PubMed E-utilities API

Source extracted via PubMed E-utilities API on 2026-04-12