The Impact of Rhodiola Rosea Extract on Strength Performance in Alternative Bench-Press and Bench-Pull Exercises Under Resting and Mental Fatigue Conditions: A Randomized, Triple-Blinded, Placebo-Controlled, Crossover Trial

Marcos-Frutos et al., 2025 | Nutrients | Rct

Citation

Marcos-Frutos Daniel, Leban Žiga, ... García-Ramos Amador. The Impact of Rhodiola Rosea Extract on Strength Performance in Alternative Bench-Press and Bench-Pull Exercises Under Resting and Mental Fatigue Conditions: A Randomized, Triple-Blinded, Placebo-Controlled, Crossover Trial. Nutrients. 2025-Mar-07;17(6). doi:10.3390/nu17060940

Abstract

Objectives: This study aimed to explore the effects of four days of Rhodiola Rosea (RR) supplementation on bench-press and bench-pull exercises under resting or mental fatigue conditions in young healthy individuals. Methods: Eighteen participants (seven women) visited the laboratory on five occasions separated by 7 days-one preliminary session and four experimental sessions. In the preliminary session, participants were familiarised with the Stroop and Multiple Object Tracking tests, after which their one-repetition maximum loads for bench presses and bench pulls were determined. The four experimental sessions had the same protocol, differing only in the supplement (RR or placebo) and mental task conditions (Stroop test or control video). Participants were assigned randomly and counterbalanced to each experimental condition: (I) RR and Stroop test, (II) RR and control video, (III) placebo and Stroop test, and (IV) placebo and control video. Results: The main findings indicate that RR supplementation has trivial-to-small effects in terms of mental fatigue, visuo-cognitive processing, or perceived exertion. However, RR was significantly superior to placebo on strength performance in the control video condition during some sets, as it increased the number of repetitions performed in the bench press and the fastest velocity in the bench pull. Out of 52 comparisons, 17 small effect sizes were observed, with 14 favouring RR and 3 favouring placebo, with the remaining differences being trivial. Conclusions: These results suggest that short-term RR supplementation is safe and provides its main ergogenic effects on physical performance rather than in visuo-cognitive or mental outcomes.

Key Findings

The main findings indicate that RR supplementation has trivial-to-small effects in terms of mental fatigue, visuo-cognitive processing, or perceived exertion. However, RR was significantly superior to placebo on strength performance in the control video condition during some sets, as it increased the number of repetitions performed in the bench press and the fastest velocity in the bench pull. Out of 52 comparisons, 17 small effect sizes were observed, with 14 favouring RR and 3 favouring placeb

Outcomes Measured

  • Requires manual extraction

Population

Field Value
Population young healthy
Sample Size See abstract
Age Range See abstract
Condition cognitive

MeSH Terms

  • Humans
  • Rhodiola
  • Female
  • Mental Fatigue
  • Male
  • Plant Extracts
  • Young Adult
  • Cross-Over Studies
  • Adult
  • Dietary Supplements
  • Muscle Strength
  • Resistance Training
  • Double-Blind Method
  • Stroop Test
  • Rest

Evidence Classification

  • Level: Rct
  • Publication Types: Journal Article, Randomized Controlled Trial
  • Vertical: rhodiola-fatigue

Provenance


Source extracted via PubMed E-utilities API on 2026-04-09