Effects of Omega-3 fatty acids supplementation and resistance training on skeletal muscle

Uchida et al., 2024 | Clin Nutr ESPEN | Meta Analysis

Citation

Uchida Yuta, Tsuji Katsunori, Ochi Eisuke. Effects of Omega-3 fatty acids supplementation and resistance training on skeletal muscle. Clin Nutr ESPEN. 2024-Jun;61:189-196. doi:10.1016/j.clnesp.2024.03.019

Abstract

BACKGROUND & AIMS: The aim of this study was to investigate the omega-3 fatty acids supplementation, and resistance training on muscle strength and mass. METHODS: A review was conducted by searching relevant randomized controlled trials investigating the effects of omega-3 fatty acids supplementation and resistance training on skeletal muscle strength and mass. Three experts independently performed a thorough examination of the literature database and conducted the systematic review and meta-analysis. RESULTS: Four studies were ultimately included in the systematic review after screening. The results of the meta-analysis revealed that the supplementation of omega-3 fatty acids and resistance training significantly improved muscle strength compared to the placebo-controlled group. However, no significant effects were observed in the effect for muscle mass. CONCLUSIONS: The interventions of omega-3 fatty acids supplementation and resistance training show promise as a countermeasure against muscular dysfunction. While further research is warranted to investigate its effects on skeletal muscle mass, the findings of this study hold implications for maintaining and/or improving the quality of life to elderly people.

Key Findings

Four studies were ultimately included in the systematic review after screening. The results of the meta-analysis revealed that the supplementation of omega-3 fatty acids and resistance training significantly improved muscle strength compared to the placebo-controlled group. However, no significant effects were observed in the effect for muscle mass.

Outcomes Measured

  • Requires manual extraction

Population

Field Value
Population See abstract
Sample Size See abstract
Age Range See abstract
Condition See abstract

MeSH Terms

  • Humans
  • Fatty Acids, Omega-3
  • Resistance Training
  • Muscle, Skeletal
  • Dietary Supplements
  • Muscle Strength
  • Randomized Controlled Trials as Topic
  • Quality of Life

Evidence Classification

  • Level: Meta Analysis
  • Publication Types: Journal Article, Systematic Review, Meta-Analysis
  • Vertical: omega-3

Provenance


Source extracted via PubMed E-utilities API on 2026-04-09