Sodium L-Aspartate Supplementation Improves Repeated-Sprint Performance

source extracted confidence: high 2026-04-09
#male #humans #aspartic-acid #exercise #dietary-supplements

Sodium L-Aspartate Supplementation Improves Repeated-Sprint Performance

Yamaguchi et al., 2023 | Nutrients | Rct

Citation

Yamaguchi Keiichi, Hayashi Nanako, ... Goto Kazushige. Sodium L-Aspartate Supplementation Improves Repeated-Sprint Performance. Nutrients. 2023-Dec-15;15(24). doi:10.3390/nu15245117

Abstract

Aspartate supplementation has been reported to improve endurance performance by facilitating the tricarboxylic acid cycle flux. The present study was performed to investigate the effects of aspartate supplementation on repeated-sprint performance and blood pH. Following an overnight fast, fourteen healthy males completed three sets of 10 × 6 s maximal sprints after consuming sodium L-aspartate (ASP) or placebo (PLA), in a double-blind manner. Both supplements were taken twice on each test day (2 × 4.5 g). Exercise performance (e.g., cadence and power output) and blood variables (e.g., pH and plasma amino acid levels) were measured. The ASP trial evidenced significantly higher plasma aspartate concentration during the first (ASP, 45.3 ± 9.2 μM; PLA, 6.1 ± 0.8 μM) and the second exercise sets (ASP, 24.2 ± 4.5 μM; PLA, 6.6 ± 0.9 μM) and peak cadence during the second set (ASP, 153 ± 3 rpm; PLA, 152 ± 3 rpm) compared with the PLA trial (all p < 0.05). The peak power output during the second exercise set (ASP, 743 ± 32 W; PLA, 734 ± 31 W; p = 0.060) and the blood pH immediately before (ASP, 7.280 ± 0.020; PLA, 7.248 ± 0.016; p = 0.087) and after the third exercise set (ASP, 7.274 ± 0.019; PLA, 7.242 ± 0.018; p = 0.093) tended to be higher in the ASP than in the PLA trial. In conclusion, ASP supplementation partially improved repeated-sprint performance (peak cadence during the second exercise set). However, it did not affect the mean power output.

Key Findings

However, it did not affect the mean power output.

Outcomes Measured

  • Requires manual extraction

Population

Field Value
Population See abstract
Sample Size See abstract
Age Range See abstract
Condition See abstract

MeSH Terms

  • Male
  • Humans
  • Aspartic Acid
  • Exercise
  • Dietary Supplements
  • Double-Blind Method
  • Sodium
  • Polyesters
  • Athletic Performance
  • Exercise Test

Evidence Classification

  • Level: Rct
  • Publication Types: Randomized Controlled Trial, Journal Article
  • Vertical: electrolytes

Provenance

Source extracted via PubMed E-utilities API on 2026-04-10