Natural remedies for Alzheimer's disease: A systematic review of randomized controlled trials

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#humans #alzheimer-disease #randomized-controlled-trials-as-topic #plants-medicinal #phytotherapy

Natural remedies for Alzheimer's disease: A systematic review of randomized controlled trials

Ahmad et al., 2023 | Metab Brain Dis | Systematic Review

Citation

Ahmad Saara, Ahmed Saad Bilal, ... Gilani Anwar-Ul-Hassan. Natural remedies for Alzheimer's disease: A systematic review of randomized controlled trials. Metab Brain Dis. 2023-Jan;38(1):17-44. doi:10.1007/s11011-022-01063-9

Abstract

Alzheimer's disease (AD) is the common type of dementia and is currently incurable. Existing FDA-approved AD drugs may not be effective for everyone, they cannot cure the disease nor stop its progression and their effects diminish over time. Therefore, the present review aimed to explore the role of natural alternatives in the treatment of AD. A systematic search was conducted using Ovid MEDLINE, CINAHL, Cochrane and PubMed databases and reference lists up to November 30, 2021. Only randomized control trials were included and appraised using the National Institute of Health framework. Data analysis showed that herbs like Gingko Biloba, Melissa Officinalis, Salvia officinalis, Ginseng and saffron alone or in combination with curcumin, low-fat diet, NuAD-Trail, and soy lecithin showed significant positive effects on AD. Moreover, combination of natural and pharmaceuticals has far better effects than only allopathic treatment. Thus, different herbal remedies in combination with FDA approved drugs are effective and more promising in treatment of AD.

Key Findings

Thus, different herbal remedies in combination with FDA approved drugs are effective and more promising in treatment of AD.

Outcomes Measured

  • Requires manual extraction

Population

Field Value
Population See abstract
Sample Size See abstract
Age Range See abstract
Condition See abstract

MeSH Terms

  • Humans
  • Alzheimer Disease
  • Randomized Controlled Trials as Topic
  • Plants, Medicinal
  • Phytotherapy

Evidence Classification

  • Level: Systematic Review
  • Publication Types: Journal Article, Systematic Review
  • Vertical: curcumin

Provenance

Source extracted via PubMed E-utilities API on 2026-04-09