Creatine supplementation and aging musculoskeletal health
Creatine supplementation and aging musculoskeletal health
Candow et al., 2014 | Endocrine | Meta Analysis
Citation
Candow Darren G, Chilibeck Philip D, Forbes Scott C. Creatine supplementation and aging musculoskeletal health. Endocrine. 2014-Apr;45(3):354-61. doi:10.1007/s12020-013-0070-4
Abstract
Sarcopenia refers to the progressive loss of muscle mass and muscle function and is a contributing factor for cachexia, bone loss, and frailty. Resistance training produces several physiological adaptations which improve aging musculoskeletal health, such as increased muscle and bone mass and strength. The combination of creatine supplementation and resistance training may further lead to greater physiological benefits. We performed meta-analyses which indicate creatine supplementation combined with resistance training has a positive effect on aging muscle mass and upper body strength compared to resistance training alone. Creatine also shows promise for improving bone mineral density and indices of bone biology. The combination of creatine supplementation and resistance training could be an effective intervention to improve aging musculoskeletal health.
Key Findings
The combination of creatine supplementation and resistance training could be an effective intervention to improve aging musculoskeletal health.
Outcomes Measured
- Requires manual extraction
Population
| Field | Value |
|---|---|
| Population | See abstract |
| Sample Size | See abstract |
| Age Range | See abstract |
| Condition | See abstract |
MeSH Terms
- Aging
- Creatine
- Humans
- Osteoporosis
- Resistance Training
- Sarcopenia
Evidence Classification
- Level: Meta Analysis
- Publication Types: Journal Article, Meta-Analysis, Review
- Vertical: creatine-aging
Provenance
- PMID: 24190049
- DOI: 10.1007/s12020-013-0070-4
- PMCID: Not in PMC
- Verified: 2026-04-09 via PubMed E-utilities API
Source extracted via PubMed E-utilities API on 2026-04-09