Do not combine without physician supervision. If you are already taking both Vitamin K and Anticoagulants, contact your healthcare provider today. Do not stop any medication without professional guidance.
Vitamin K × Anticoagulants
CRITICAL
Well-Established Evidence
Mechanism
Vitamin K antagonizes the effect of all vitamin K antagonist anticoagulants (warfarin, acenocoumarol, phenprocoumon).
Effect
Reduced anticoagulant effect; increased thrombosis risk
Management
Avoid vitamin K supplements. Maintain consistent dietary vitamin K intake.
Plain Language Summary
AI-generated · Qwen 3.6 · grounded in 2 sources · methodologyThis combination is dangerous. Taking Vitamin K supplements can interfere with how blood-thinning medications work, which increases the risk of developing blood clots.
Source
FDA warfarin labeling; Holbrook AM et al. Ann Intern Med 2005
Research
Supporting Research
Antiplatelet and anticoagulant agents for secondary prevention of stroke and other thromboembolic events in people with antiphospholipid syndrome
Anticoagulants (extended duration) for prevention of venous thromboembolism following total hip or knee replacement or hip fracture repair
Antiplatelet and anticoagulant agents for secondary prevention of stroke and other thromboembolic events in people with antiphospholipid syndrome
Direct factor Xa inhibitors versus low molecular weight heparins or vitamin K antagonists for prevention of venous thromboembolism in elective primary hip or knee replacement or hip fracture repair
Factor Xa inhibitors versus vitamin K antagonists for preventing cerebral or systemic embolism in patients with atrial fibrillation
Antiplatelet agents and anticoagulants for hypertension
Primary prophylaxis for venous thromboembolism in ambulatory cancer patients receiving chemotherapy
Factor Xa inhibitors versus vitamin K antagonists for preventing cerebral or systemic embolism in patients with atrial fibrillation
Medical Disclaimer: This interaction record is for informational and educational purposes only and does not constitute medical advice. Always consult your healthcare provider or pharmacist before combining any supplement with prescription medications.