⚠️ Mechanism
Interaction identified from DDInter 2.0 database. Specific drugs: Defibrotide
📋 Effect
See mechanism description
💊 Management
Consult healthcare provider before combining.
Plain Language Summary
This combination is considered moderately risky. There is a known interaction between Vitamin E and Defibrotide, and it is recommended to consult a healthcare provider before using them together.
Source
DDInter 2.0 (ddinter.scbdd.com)
Supporting Research
Exercise for intermittent claudication
Effects of vitamin E supplementation on the risk and progression of AD: a systematic review and meta-analysis
Effect of vitamin E supplementation in rheumatoid arthritis: a systematic review and meta-analysis
Vitamin, Mineral, and Multivitamin Supplementation to Prevent Cardiovascular Disease and Cancer: US Preventive Services Task Force Recommendation Statement.
Antioxidants for chronic kidney disease
Exercise for intermittent claudication
Treatment for cramps in amyotrophic lateral sclerosis/motor neuron disease
Association of blood antioxidants and vitamins with risk of age-related cataract: a meta-analysis of observational studies
Medical Disclaimer: This interaction record is for informational and educational purposes only and does not constitute medical advice. Drug-supplement interactions can be dangerous. Always consult your healthcare provider or pharmacist before combining any supplement with prescription medications. Do not stop or change any medication without professional guidance.