🟡

Vitamin E × Bivalirudin

MODERATE INTERACTION

⚠️ Mechanism

Interaction identified from DDInter 2.0 database. Specific drugs: Bivalirudin

📋 Effect

See mechanism description

💊 Management

Consult healthcare provider before combining.

Plain Language Summary

This combination is considered moderately risky. Taking Vitamin E while using Bivalirudin may increase your risk of bleeding.

Source

DDInter 2.0 (ddinter.scbdd.com)

Supporting Research

Exercise for intermittent claudication PMID:29278423 DOI:10.1002/14651858.CD000990.pub4 2017
Effects of vitamin E supplementation on the risk and progression of AD: a systematic review and meta-analysis PMID:30900960 DOI:10.1080/1028415X.2019.1585506 2021
Effect of vitamin E supplementation in rheumatoid arthritis: a systematic review and meta-analysis PMID:35468933 DOI:10.1038/s41430-022-01148-9 2023
Vitamin, Mineral, and Multivitamin Supplementation to Prevent Cardiovascular Disease and Cancer: US Preventive Services Task Force Recommendation Statement. PMID:35727271 DOI:10.1001/jama.2022.8970 2022
Antioxidants for chronic kidney disease PMID:23076940 DOI:10.1002/14651858.CD008176.pub2 2012
Exercise for intermittent claudication PMID:25037027 DOI:10.1002/14651858.CD000990.pub3 2014
Treatment for cramps in amyotrophic lateral sclerosis/motor neuron disease PMID:22513921 DOI:10.1002/14651858.CD004157.pub2 2012
Association of blood antioxidants and vitamins with risk of age-related cataract: a meta-analysis of observational studies PMID:23842458 DOI:10.3945/ajcn.112.053835 2013
Medical Disclaimer: This interaction record is for informational and educational purposes only and does not constitute medical advice. Drug-supplement interactions can be dangerous. Always consult your healthcare provider or pharmacist before combining any supplement with prescription medications. Do not stop or change any medication without professional guidance.