⚠️ Mechanism
Interaction identified from DDInter 2.0 database. Specific drugs: Cyproheptadine
📋 Effect
See mechanism description
💊 Management
Consult healthcare provider before combining.
Plain Language Summary
This combination may be unsafe because it can significantly increase drowsiness. Taking Valerian and Cyproheptadine together may cause a much stronger sedative effect than either one alone.
Source
DDInter 2.0 (ddinter.scbdd.com)
Supporting Research
Non-pharmacological interventions for sleep promotion in the intensive care unit
Effectiveness and safety of oral sedation in adult patients undergoing dental procedures: a systematic review
Herbal medicine for insomnia: A systematic review and meta-analysis
Effects of Dietary Supplementation in Patients with Restless Legs Syndrome: A Systematic Review
Herbal Remedies and Their Possible Effect on the GABAergic System and Sleep
Herbal medicines in children with attention deficit hyperactivity disorder (ADHD): A systematic review
Relationship between concentrations of microbiological agents in the air of agricultural settings and occurrence of work-related symptoms in exposed persons
A systematic review of insomnia and complementary medicine
Medical Disclaimer: This interaction record is for informational and educational purposes only and does not constitute medical advice. Drug-supplement interactions can be dangerous. Always consult your healthcare provider or pharmacist before combining any supplement with prescription medications. Do not stop or change any medication without professional guidance.