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Saw Palmetto × Anticoagulants

MINOR INTERACTION — Possible Evidence

⚠️ Mechanism

Saw palmetto may have mild antiplatelet properties, though evidence is weak.

📋 Effect

Possible minor increased bleeding risk

💊 Management

Monitor INR if on warfarin. Minor clinical concern at typical doses.

Plain Language Summary

This combination is considered a minor concern rather than a major danger. Saw palmetto may slightly increase your risk of bleeding when taken with blood-thinning medications.

Source

Yale SH, Glurich I. J Herb Pharmacother 2005

Supporting Research

Serenoa repens for benign prostatic hyperplasia PMID:19370565 DOI:10.1002/14651858.CD001423.pub2 2009
Serenoa repens for benign prostatic hyperplasia PMID:23235581 DOI:10.1002/14651858.CD001423.pub3 2012
Non-hormonal treatment for male infertility: the potential role of Serenoa repens, selenium and lycopene PMID:31002161 DOI:10.26355/eurrev_201904_17595 2019
Comparison of Serenoa repens With Tamsulosin in the Treatment of Benign Prostatic Hyperplasia: A Systematic Review and Meta-Analysis PMID:32274957 DOI:10.1177/1557988320905407 2020
Effects of dietary supplements on androgenetic alopecia: a systematic review and network meta-analysis PMID:41561175 DOI:10.3389/fnut.2025.1719711 2025
Benign prostate hyperplasia and nutrition PMID:31451276 DOI:10.1016/j.clnesp.2019.07.015 2019
American palm ethnomedicine: a meta-analysis PMID:20034398 DOI:10.1186/1746-4269-5-43 2009
Benign prostatic hyperplasia and male lower urinary tract symptoms (LUTS) PMID:21871136 2011
Medical Disclaimer: This interaction record is for informational and educational purposes only and does not constitute medical advice. Drug-supplement interactions can be dangerous. Always consult your healthcare provider or pharmacist before combining any supplement with prescription medications. Do not stop or change any medication without professional guidance.