Home/ Interactions/ Saw Palmetto × Antiandrogens

Saw Palmetto × Antiandrogens

MINOR Possible Evidence

Mechanism

Saw palmetto has antiandrogenic properties, potentially additive with drugs like finasteride or flutamide.

Effect

Possible additive antiandrogenic effect

Management

Monitor for additive effects. Generally safe but may enhance drug effect.

Plain Language Summary

✨ AI-generated · Qwen 3.6 · grounded in 2 sources · methodology

This combination is generally considered safe, but it may increase the effects of your medication. Because both Saw Palmetto and antiandrogens work to lower certain hormones, taking them together could potentially enhance the drug's impact.

Source

Prager N et al. J Urol 2002; Gerber GS et al. Urology 2001

Research

Supporting Research

Serenoa repens for benign prostatic hyperplasia
PMID:19370565 DOI 2009
Serenoa repens for benign prostatic hyperplasia
PMID:23235581 DOI 2012
Non-hormonal treatment for male infertility: the potential role of Serenoa repens, selenium and lycopene
PMID:31002161 DOI 2019
Comparison of Serenoa repens With Tamsulosin in the Treatment of Benign Prostatic Hyperplasia: A Systematic Review and Meta-Analysis
PMID:32274957 DOI 2020
Effects of dietary supplements on androgenetic alopecia: a systematic review and network meta-analysis
PMID:41561175 DOI 2025
Benign prostate hyperplasia and nutrition
PMID:31451276 DOI 2019
American palm ethnomedicine: a meta-analysis
PMID:20034398 DOI 2009
Benign prostatic hyperplasia and male lower urinary tract symptoms (LUTS)
PMID:21871136 2011
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Medical Disclaimer: This interaction record is for informational and educational purposes only and does not constitute medical advice. Always consult your healthcare provider or pharmacist before combining any supplement with prescription medications.