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Melatonin × Iron Chelators

MODERATE INTERACTION

⚠️ Mechanism

Interaction identified from DDInter 2.0 database. Specific drugs: Deferasirox

📋 Effect

See mechanism description

💊 Management

Consult healthcare provider before combining.

Plain Language Summary

This combination is considered moderately risky. An interaction has been identified between melatonin and iron chelators such as deferasirox.

Source

DDInter 2.0 (ddinter.scbdd.com)

Supporting Research

Interventions for preventing delirium in hospitalised non-ICU patients PMID:26967259 DOI:10.1002/14651858.CD005563.pub3 2016
Effect of melatonin on quality of life and symptoms in patients with cancer: a systematic review and meta-analysis of randomised controlled trials PMID:36104141 DOI:10.1136/bmjopen-2022-060912 2022
Pharmacological interventions for prevention of weight gain in people with schizophrenia PMID:36190739 DOI:10.1002/14651858.CD013337.pub2 2022
Prevention of depression in adults with long-term physical conditions PMID:33667319 DOI:10.1002/14651858.CD011246.pub2 2021
Comparative effects of pharmacological interventions for the acute and long-term management of insomnia disorder in adults: a systematic review and network meta-analysis PMID:35843245 DOI:10.1016/S0140-6736(22)00878-9 2022
Does melatonin administration reduce the incidence of postoperative delirium in adults? Systematic review and meta-analysis PMID:36990485 DOI:10.1136/bmjopen-2022-069950 2023
Second-generation antidepressants for preventing seasonal affective disorder in adults PMID:26558418 DOI:10.1002/14651858.CD011268.pub2 2015
Interventions for preventing type 2 diabetes in adults with mental disorders in low- and middle-income countries PMID:33591592 DOI:10.1002/14651858.CD013281.pub2 2021
Medical Disclaimer: This interaction record is for informational and educational purposes only and does not constitute medical advice. Drug-supplement interactions can be dangerous. Always consult your healthcare provider or pharmacist before combining any supplement with prescription medications. Do not stop or change any medication without professional guidance.