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Melatonin × Antiplatelet Drugs

MODERATE INTERACTION

⚠️ Mechanism

Interaction identified from DDInter 2.0 database. Specific drugs: Anagrelide

📋 Effect

See mechanism description

💊 Management

Consult healthcare provider before combining.

Plain Language Summary

This combination carries a moderate risk. Taking melatonin with certain antiplatelet drugs, such as anagrelide, may increase your risk of bleeding.

Source

DDInter 2.0 (ddinter.scbdd.com)

Supporting Research

Interventions for preventing delirium in hospitalised non-ICU patients PMID:26967259 DOI:10.1002/14651858.CD005563.pub3 2016
Effect of melatonin on quality of life and symptoms in patients with cancer: a systematic review and meta-analysis of randomised controlled trials PMID:36104141 DOI:10.1136/bmjopen-2022-060912 2022
Pharmacological interventions for prevention of weight gain in people with schizophrenia PMID:36190739 DOI:10.1002/14651858.CD013337.pub2 2022
Prevention of depression in adults with long-term physical conditions PMID:33667319 DOI:10.1002/14651858.CD011246.pub2 2021
Comparative effects of pharmacological interventions for the acute and long-term management of insomnia disorder in adults: a systematic review and network meta-analysis PMID:35843245 DOI:10.1016/S0140-6736(22)00878-9 2022
Does melatonin administration reduce the incidence of postoperative delirium in adults? Systematic review and meta-analysis PMID:36990485 DOI:10.1136/bmjopen-2022-069950 2023
Second-generation antidepressants for preventing seasonal affective disorder in adults PMID:26558418 DOI:10.1002/14651858.CD011268.pub2 2015
Interventions for preventing type 2 diabetes in adults with mental disorders in low- and middle-income countries PMID:33591592 DOI:10.1002/14651858.CD013281.pub2 2021
Medical Disclaimer: This interaction record is for informational and educational purposes only and does not constitute medical advice. Drug-supplement interactions can be dangerous. Always consult your healthcare provider or pharmacist before combining any supplement with prescription medications. Do not stop or change any medication without professional guidance.