Magnesium × Antihypertensives
MINOR
Possible Evidence
Mechanism
Magnesium has mild vasodilatory effects, potentially additive with antihypertensive medications.
Effect
Possible additive blood pressure reduction
Management
Monitor blood pressure. Generally beneficial interaction. May allow lower drug doses.
Plain Language Summary
AI-generated · Qwen 3.6 · grounded in 2 sources · methodologyThis combination is generally considered safe. Magnesium can help relax blood vessels, which may work alongside blood pressure medications to further lower blood pressure.
Source
Kass L et al. Eur J Clin Nutr 2012
Research
Supporting Research
The association between circulating magnesium and clinically relevant outcomes in patients with chronic kidney disease: A systematic review and meta-analysis
Interventions for preventing post-operative atrial fibrillation in patients undergoing heart surgery
Association between Serum Magnesium and Fractures: A Systematic Review and Meta-Analysis of Observational Studies
A meta-analysis of methane-mitigation potential of feed additives evaluated in vitro
Dietary Approaches to Stop Hypertension (DASH) for the primary and secondary prevention of cardiovascular diseases
Circulating and dietary magnesium and risk of cardiovascular disease: a systematic review and meta-analysis of prospective studies
Inhaled magnesium sulfate in the treatment of acute asthma
Pharmacological interventions for benzodiazepine discontinuation in chronic benzodiazepine users
Medical Disclaimer: This interaction record is for informational and educational purposes only and does not constitute medical advice. Always consult your healthcare provider or pharmacist before combining any supplement with prescription medications.