⚠️ Mechanism
Interaction identified from DDInter 2.0 database. Specific drugs: Difenoxin
📋 Effect
See mechanism description
💊 Management
Consult healthcare provider before combining.
Plain Language Summary
This combination is considered moderately risky because a known interaction exists between Kava and Difenoxin. You should consult your healthcare provider before using these two together.
Source
DDInter 2.0 (ddinter.scbdd.com)
Supporting Research
Kava in generalized anxiety disorder: three placebo-controlled trials
Explanatory attributions of anxiety and recovery in a study of kava
Kava-Kava administration reduces anxiety in perimenopausal women
Kava treatment in patients with anxiety
Efficacy of kava-kava in the treatment of non-psychotic anxiety, following pretreatment with benzodiazepines
Medical Disclaimer: This interaction record is for informational and educational purposes only and does not constitute medical advice. Drug-supplement interactions can be dangerous. Always consult your healthcare provider or pharmacist before combining any supplement with prescription medications. Do not stop or change any medication without professional guidance.