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Ginkgo × Warfarin

MODERATE INTERACTION — Probable Evidence

⚠️ Mechanism

Ginkgolides inhibit platelet-activating factor, potentially additive with warfarin.

📋 Effect

Increased bleeding risk

💊 Management

Monitor INR and for signs of bleeding. Avoid combined use if possible.

Plain Language Summary

This combination can be dangerous because it may increase your risk of bleeding. Ginkgo can affect how your blood cells clump together, which can add to the blood-thinning effects of warfarin.

Source

Engelsen J et al. Thromb Haemost 2002

Supporting Research

Ginkgo biloba for cognitive impairment and dementia PMID:41641880 DOI:10.1002/14651858.CD013661.pub2 2026
Ginkgo biloba for cognitive impairment and dementia PMID:19160216 DOI:10.1002/14651858.CD003120.pub3 2009
Ginkgo biloba for tinnitus PMID:23543524 DOI:10.1002/14651858.CD003852.pub3 2013
Ginkgo biloba for tinnitus PMID:36383762 DOI:10.1002/14651858.CD013514.pub2 2022
Ginkgo biloba for intermittent claudication PMID:23744597 DOI:10.1002/14651858.CD006888.pub3 2013
The Comparative Efficacy of Multiple Interventions for Mild Cognitive Impairment in Alzheimer's Disease: A Bayesian Network Meta-Analysis PMID:32581760 DOI:10.3389/fnagi.2020.00121 2020
Comparative effects of Bacopa monnieri and Ginkgo biloba on cognitive functions: A systematic review and network meta-analysis PMID:41678913 DOI:10.1016/j.phymed.2026.157915 2026
Ginkgo biloba for intermittent claudication PMID:19370657 DOI:10.1002/14651858.CD006888.pub2 2009
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Medical Disclaimer: This interaction record is for informational and educational purposes only and does not constitute medical advice. Drug-supplement interactions can be dangerous. Always consult your healthcare provider or pharmacist before combining any supplement with prescription medications. Do not stop or change any medication without professional guidance.