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Ginkgo × Anticonvulsants

MODERATE INTERACTION — Probable Evidence

⚠️ Mechanism

Ginkgo may lower seizure threshold, potentially counteracting anticonvulsant drugs.

📋 Effect

Reduced seizure control; possible breakthrough seizures

💊 Management

Avoid ginkgo in patients with epilepsy or on anticonvulsants.

Plain Language Summary

This combination can be dangerous because Ginkgo may interfere with how well anticonvulsant medications work. This could make it harder to control seizures and may lead to more frequent seizure activity.

Source

Granger AS. BMJ 2001; Gregory P. Aust Fam Physician 2005

Supporting Research

Ginkgo biloba for cognitive impairment and dementia PMID:41641880 DOI:10.1002/14651858.CD013661.pub2 2026
Ginkgo biloba for cognitive impairment and dementia PMID:19160216 DOI:10.1002/14651858.CD003120.pub3 2009
Ginkgo biloba for tinnitus PMID:23543524 DOI:10.1002/14651858.CD003852.pub3 2013
Ginkgo biloba for tinnitus PMID:36383762 DOI:10.1002/14651858.CD013514.pub2 2022
Ginkgo biloba for intermittent claudication PMID:23744597 DOI:10.1002/14651858.CD006888.pub3 2013
The Comparative Efficacy of Multiple Interventions for Mild Cognitive Impairment in Alzheimer's Disease: A Bayesian Network Meta-Analysis PMID:32581760 DOI:10.3389/fnagi.2020.00121 2020
Comparative effects of Bacopa monnieri and Ginkgo biloba on cognitive functions: A systematic review and network meta-analysis PMID:41678913 DOI:10.1016/j.phymed.2026.157915 2026
Ginkgo biloba for intermittent claudication PMID:19370657 DOI:10.1002/14651858.CD006888.pub2 2009
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Medical Disclaimer: This interaction record is for informational and educational purposes only and does not constitute medical advice. Drug-supplement interactions can be dangerous. Always consult your healthcare provider or pharmacist before combining any supplement with prescription medications. Do not stop or change any medication without professional guidance.