⚠️ Mechanism
Garlic may have antiplatelet properties that add to warfarin's anticoagulant effect.
📋 Effect
Increased bleeding risk
💊 Management
Monitor INR and bleeding signs. Avoid high-dose garlic supplements.
Plain Language Summary
This combination can be risky because garlic may increase the blood-thinning effects of warfarin. This can lead to an increased risk of bleeding.
Source
Vaes LP, Chyka PA. Am J Health Syst Pharm 2002
Supporting Research
Garlic supplementation for the treatment of chronic liver disease: a meta-analysis of randomized controlled trials
Consumption of large amounts of Allium vegetables reduces risk for gastric cancer in a meta-analysis
Garlic for the common cold
Effects of Garlic Supplementation on Cardiovascular Risk Factors in Adults: A Comprehensive Updated Systematic Review and Meta-Analysis of Randomized Controlled Trials
Effects of seasoning on the formation of heterocyclic amines and polycyclic aromatic hydrocarbons in meats: A meta-analysis
A Systematic Review and Meta-Analysis of Ayurvedic Herbal Preparations for Hypercholesterolemia
Garlic intake lowers fasting blood glucose: meta-analysis of randomized controlled trials
Garlic for the common cold
Medical Disclaimer: This interaction record is for informational and educational purposes only and does not constitute medical advice. Drug-supplement interactions can be dangerous. Always consult your healthcare provider or pharmacist before combining any supplement with prescription medications. Do not stop or change any medication without professional guidance.