⚠️ Mechanism
Garlic has antiplatelet properties that may add to antiplatelet drug effects.
📋 Effect
Increased bleeding risk
💊 Management
Avoid high-dose garlic supplements with antiplatelet drugs (aspirin, clopidogrel). Stop 7 days before surgery.
Plain Language Summary
This combination can be risky because it increases your chance of bleeding. Garlic can work similarly to antiplatelet drugs, which may cause your blood to become even thinner.
Source
Bordia A et al. Prostaglandins Leukot Essent Fatty Acids 1998
Supporting Research
Garlic supplementation for the treatment of chronic liver disease: a meta-analysis of randomized controlled trials
Consumption of large amounts of Allium vegetables reduces risk for gastric cancer in a meta-analysis
Garlic for the common cold
Effects of Garlic Supplementation on Cardiovascular Risk Factors in Adults: A Comprehensive Updated Systematic Review and Meta-Analysis of Randomized Controlled Trials
Effects of seasoning on the formation of heterocyclic amines and polycyclic aromatic hydrocarbons in meats: A meta-analysis
A Systematic Review and Meta-Analysis of Ayurvedic Herbal Preparations for Hypercholesterolemia
Garlic intake lowers fasting blood glucose: meta-analysis of randomized controlled trials
Garlic for the common cold
Medical Disclaimer: This interaction record is for informational and educational purposes only and does not constitute medical advice. Drug-supplement interactions can be dangerous. Always consult your healthcare provider or pharmacist before combining any supplement with prescription medications. Do not stop or change any medication without professional guidance.