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Antioxidants × Chemotherapy

MODERATE INTERACTION — Inconclusive Evidence

⚠️ Mechanism

Antioxidants (vitamin C, E, selenium, etc.) may protect tumor cells from oxidative damage caused by some chemotherapies.

📋 Effect

Possible reduction in chemotherapy efficacy

💊 Management

Avoid high-dose antioxidants during chemotherapy unless oncologist approves. Low-dose RDA-level intake is generally safe.

Plain Language Summary

Taking high doses of antioxidants during chemotherapy can be risky because they may protect tumor cells from the damage the treatment is meant to cause. This could potentially make the chemotherapy less effective.

Source

Lawenda BD et al. J Natl Cancer Inst 2008

Medical Disclaimer: This interaction record is for informational and educational purposes only and does not constitute medical advice. Drug-supplement interactions can be dangerous. Always consult your healthcare provider or pharmacist before combining any supplement with prescription medications. Do not stop or change any medication without professional guidance.