Aloe Vera × Anticoagulants
MODERATE
Possible Evidence
Mechanism
Oral aloe vera may have antiplatelet properties and increase bleeding risk.
Effect
Possible increased bleeding risk with warfarin and antiplatelet drugs
Management
Avoid oral aloe vera supplements with anticoagulants. Topical aloe is safe.
Plain Language Summary
AI-generated · Qwen 3.6 · grounded in 2 sources · methodologyThis combination can be dangerous because oral aloe vera may increase your risk of bleeding while taking blood thinners. This occurs because the supplement may interfere with the body's ability to form blood clots.
Source
Lee A et al. Br J Clin Pharmacol 2004
Research
Supporting Research
Aloe vera gel and cesarean wound healing; a randomized controlled clinical trial
Topical Aloe Vera Gel for Accelerated Wound Healing of Split-Thickness Skin Graft Donor Sites: A Double-Blind, Randomized, Controlled Trial and Systematic Review
The efficacy of aloe vera used for burn wound healing: a systematic review
PMID:17499928
2007
Effects of Aloe Sterol Supplementation on Skin Elasticity, Hydration, and Collagen Score: A 12-Week Double-Blind, Randomized, Controlled Trial
Effects of low-dose Aloe sterol supplementation on skin moisture, collagen score and objective or subjective symptoms: 12-week, double-blind, randomized controlled trial
Effectiveness of Aloe Vera gel compared with 1% silver sulphadiazine cream as burn wound dressing in second degree burns
PMID:23894900
2013
Phase III double-blind evaluation of an aloe vera gel as a prophylactic agent for radiation-induced skin toxicity
PMID:8892458
1996
Aloe vera for preventing radiation-induced skin reactions: a systematic literature review
PMID:16149293
2005
Medical Disclaimer: This interaction record is for informational and educational purposes only and does not constitute medical advice. Always consult your healthcare provider or pharmacist before combining any supplement with prescription medications.