Adverse Event Profile: Melatonin

Source: FDA Center for Food Safety and Applied Nutrition (CFSAN) Adverse Event Reporting System Total Events: 43 Serious Events: 19 Date Range: 20051201 to 20241115

Top Reported Reactions

  • Dyspnoea: 8
  • Urticaria: 4
  • Diarrhoea: 4
  • Nausea: 4
  • Abdominal pain upper: 4
  • Dizziness: 3
  • Vomiting: 3
  • Pruritus: 3
  • COLON INJURY: 2
  • Anxiety: 2
  • Constipation: 2
  • Feeling cold: 2
  • Hypoaesthesia: 2
  • Insomnia: 2
  • Tremor: 2
  • Feeling hot: 2
  • Hypersensitivity: 2
  • Agitation: 2
  • Hallucination: 2
  • Hepatic enzyme increased: 2

Outcomes

  • Other Serious or Important Medical Event: 24
  • Visited Emergency Room: 12
  • Visited a Health Care Provider: 12
  • Hospitalization: 11
  • Other Serious Outcome: 6
  • Disability: 5
  • Other Outcome: 3
  • Life Threatening: 2
  • Required Intervention: 1
  • Death: 1

Products Involved (15 unique)

  • FAST ACTING LIQUID MELATONIN
  • MELATONIN
  • MELATONIN VITACOST (MELATONIN)
  • Melatonin
  • NATURE'S BOUNTY MELATONIN
  • NATUREMADE MELATONIN
  • PURITAN'S PRIDE MELATONIN
  • SCHIFF MELATONIN PLUS
  • SPRING VALLEY MELATONIN SLEEP SUPPORT
  • SUNDOWN MELATONIN 300 MCG TABLETS
  • ZARBEE'S NATURALS CHILDREN'S SLEEP WITH MELATONIN
  • ZARBEES CHILDRENS SLEEP WITH MELATONIN NATURAL GRA
  • ZARBEES NATURALS CHILDRENS SLEEP WITH MELATONIN
  • ZZQUIL MELATONIN WITH LAVENDAR AND CHAMOMILE
  • melatonin

Disclaimer

This data is from the FDA CAERS database. A report does not mean the supplement caused the adverse event. Reports may be incomplete, duplicated, or unrelated. This is for safety awareness only.