The Choice of Hip Arthroplasty: HRA or THA? Revealed by Meta-Analysis

Fan et al., 2025 | Orthop Surg | Meta Analysis

Citation

Fan Xiao, Zhou Yimin, ... Yu Tengbo. The Choice of Hip Arthroplasty: HRA or THA? Revealed by Meta-Analysis. Orthop Surg. 2025-Jun;17(6):1577-1588. doi:10.1111/os.70019

Abstract

BACKGROUND: Total hip arthroplasty (THA) is the gold standard for end-stage hip arthrosis, while hip resurfacing arthroplasty (HRA) is considered a more bone-conserving alternative. This meta-analysis aimed to compare the safety and clinical efficacy of HRA and THA. METHODS: The databases of PubMed, EMBASE, Cochrane Library, and CNKI were searched for RCTs comparing HRA and THA in treating hip arthrosis from database initiation to April 2024. Inclusion and exclusion criteria were defined, and data extraction, quality evaluation, and risk bias assessment were performed. A meta-analysis was conducted using appropriate RevManv5.4 and Stata v14.0 software. RESULTS: Twenty RCTs from six countries were included. HRA had a similar revision rate, function scores (WOMAC, HSS, OHS, UCLA activity score, EQ-D, EQ-5D VAS), and blood levels of cobalt and chromium compared to THA. HRA had fewer complications and less blood loss but required more operating time. CONCLUSIONS: HRA is a safe and effective alternative to THA, with similar revision and functional outcomes, less blood loss, and is particularly suitable for young male patients with a demand for high-level activities.

Key Findings

Twenty RCTs from six countries were included. HRA had a similar revision rate, function scores (WOMAC, HSS, OHS, UCLA activity score, EQ-D, EQ-5D VAS), and blood levels of cobalt and chromium compared to THA. HRA had fewer complications and less blood loss but required more operating time.

Outcomes Measured

  • Requires manual extraction

Population

Field Value
Population a demand for high
Sample Size See abstract
Age Range See abstract
Condition See abstract

MeSH Terms

  • Humans
  • Arthroplasty, Replacement, Hip
  • Osteoarthritis, Hip
  • Reoperation
  • Randomized Controlled Trials as Topic

Evidence Classification

  • Level: Meta Analysis
  • Publication Types: Journal Article, Meta-Analysis, Comparative Study, Review
  • Vertical: chromium

Provenance


Source extracted via PubMed E-utilities API on 2026-04-09