Comprehensive PRISMA Based Systematic Review: Exploring the Phytochemistry, Pharmacological Profile and Clinical aspects of Panax ginseng

source extracted confidence: high 2026-04-09
#panax #humans #antineoplastic-agents-phytogenic #ginsenosides #phytochemicals

Comprehensive PRISMA Based Systematic Review: Exploring the Phytochemistry, Pharmacological Profile and Clinical aspects of Panax ginseng

Singh et al., 2025 | Curr Top Med Chem | Systematic Review

Citation

Singh Sonia, Agrawal Ronak, Sharma Himanshu. Comprehensive PRISMA Based Systematic Review: Exploring the Phytochemistry, Pharmacological Profile and Clinical aspects of Panax ginseng. Curr Top Med Chem. 2025;25(2):172-195. doi:10.2174/0115680266344493241014082257

Abstract

INTRODUCTION: Ginseng, a perennial herb belonging to the Araliaceae family, is renowned for its traditional and folk uses. The Panax ginseng C.A. Meyer species is predominantly found in Asian countries, including Japan, China, and Korea. MATERIALS AND METHODS: This manuscript offers valuable insights into the cultivation, collection, morphology, phytochemistry, pharmacological properties, and clinical studies of Ginseng. The data was meticulously gathered from diverse electronic resources, such as PubMed, Scopus, Science Direct, and Web of Science, spanning from 1963 to 2023. RESULTS: Ginseng contains various bioactive components, including carbohydrates, polyacetylenic alcohols, polysaccharides, ginsenosides, peptides, vitamins, and fatty acids. The biological attributes of ginsenosides, which include anti-diabetic, anti-cancer, anti-oxidant, and anti-inflammatory activities, render them especially remarkable. CONCLUSION: This manuscript comprehensively explores the versatile therapeutic applications of ginseng in the treatment of various types of cancers.

Key Findings

Ginseng contains various bioactive components, including carbohydrates, polyacetylenic alcohols, polysaccharides, ginsenosides, peptides, vitamins, and fatty acids. The biological attributes of ginsenosides, which include anti-diabetic, anti-cancer, anti-oxidant, and anti-inflammatory activities, render them especially remarkable.

Outcomes Measured

  • inflammatory markers

Population

Field Value
Population See abstract
Sample Size See abstract
Age Range See abstract
Condition See abstract

MeSH Terms

  • Panax
  • Humans
  • Antineoplastic Agents, Phytogenic
  • Ginsenosides
  • Phytochemicals
  • Neoplasms
  • Antioxidants
  • Animals
  • Anti-Inflammatory Agents
  • Plant Extracts

Evidence Classification

  • Level: Systematic Review
  • Publication Types: Journal Article, Systematic Review
  • Vertical: ginseng

Provenance

Source extracted via PubMed E-utilities API on 2026-04-09