Radioprotective Effect of Selenium Nanoparticles: A Mini Review

source extracted confidence: high 2026-04-09
#selenium #radiation-protective-agents #animals #humans #antioxidants

Radioprotective Effect of Selenium Nanoparticles: A Mini Review

Azmoonfar et al., 2024 | IET Nanobiotechnol | Systematic Review

Citation

Azmoonfar Rasool, Moslehi Masoud, Shahbazi-Gahrouei Daryoush. Radioprotective Effect of Selenium Nanoparticles: A Mini Review. IET Nanobiotechnol. 2024;2024:5538107. doi:10.1049/2024/5538107

Abstract

MATERIALS AND METHODS: This study followed the PRISMA reporting guidelines to present the results. A comprehensive search was performed on electronic databases such as PubMed, Scopus, Web of Sciences, and Science Direct. Initially, 413 articles were retrieved. After removing duplicates and applying specific inclusion and exclusion criteria, 10 articles were finally included in this systematic review. RESULTS: The reviewed studies showed that selenium nanoparticles had anti-inflammatory and antioxidant properties. They effectively protected the kidneys, liver, and testicles from damage. Furthermore, there was evidence of efficient radioprotection for the organs examined without significant side effects. CONCLUSIONS: This systematic review emphasizes the potential advantages of using selenium nanoparticles to prevent the negative effects of ionizing radiation. Importantly, these protective effects were achieved without causing noticeable side effects. These findings suggest the potential role of selenium nanoparticles as radioprotective agents, offering possible therapeutic applications to reduce the risks related to ionizing radiation exposure in medical imaging and radiotherapy procedures.

Key Findings

The reviewed studies showed that selenium nanoparticles had anti-inflammatory and antioxidant properties. They effectively protected the kidneys, liver, and testicles from damage. Furthermore, there was evidence of efficient radioprotection for the organs examined without significant side effects.

Outcomes Measured

  • inflammatory markers

Population

Field Value
Population See abstract
Sample Size See abstract
Age Range See abstract
Condition See abstract

MeSH Terms

  • Selenium
  • Radiation-Protective Agents
  • Animals
  • Humans
  • Antioxidants
  • Nanoparticles
  • Metal Nanoparticles
  • Radiation Injuries

Evidence Classification

  • Level: Systematic Review
  • Publication Types: Journal Article, Systematic Review
  • Vertical: selenium

Provenance

Source extracted via PubMed E-utilities API on 2026-04-09