The favorable impacts of cardamom on related complications of diabetes: A comprehensive literature systematic review

source extracted confidence: high 2026-04-09
#animals #humans #elettaria #diabetes-mellitus-type-2 #dyslipidemias

The favorable impacts of cardamom on related complications of diabetes: A comprehensive literature systematic review

Nasimi et al., 2024 | Diabetes Metab Syndr | Systematic Review

Citation

Nasimi Doost Azgomi Ramin, Karimi Arash, Moini Jazani Arezoo. The favorable impacts of cardamom on related complications of diabetes: A comprehensive literature systematic review. Diabetes Metab Syndr. 2024-Feb;18(2):102947. doi:10.1016/j.dsx.2024.102947

Abstract

BACKGROUND AND AIM: Complementary and alternative medicine plays an increasing role in preventing, and regulatory, complications associated with diabetes. There are plenty of polyphenolic compounds found in Elettaria cardamomum (Cardamom) such as luteolin, limonene, pelargonidin, caffeic acid, kaempferol, gallic acid, and quercetin which can be used in many metabolic diseases. METHOD: The objective of this systematic review was to appraise evidence from clinical and in vivo studies on the effects of cardamom on inflammation, blood glucose, oxidative stress and dyslipidemia of diabetes mellitus. According to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statements, the present study was carried out. Studies were conducted by searching databases such as EMBASE, Scopus, PubMed, Google Scholar, web of sciences, and Cochrane Library from the commencement until April 2022. RESULTS: All available human and animal studies examining the effects of cardamom on diabetes were published in the form of English articles. Finally, only 14 of the 241 articles met the criteria for analysis. Of the 14 articles, 8 were in vivo studies, and 6 were clinical trial studies. Most studies have indicated the beneficial effects of cardamom on insulin resistance, oxidative stress and inflammation. Cardamom also improved dyslipidemia, but had no substantial effect on weight loss. CONCLUSION: According to most studies, cardamom supplementation enhanced antioxidant enzyme production and activity in diabetes mellitus and decreased oxidative stress and inflammatory factors. Despite this, the exact mechanism of the disease needs to be identified through more clinical trials.

Key Findings

All available human and animal studies examining the effects of cardamom on diabetes were published in the form of English articles. Finally, only 14 of the 241 articles met the criteria for analysis. Of the 14 articles, 8 were in vivo studies, and 6 were clinical trial studies. Most studies have indicated the beneficial effects of cardamom on insulin resistance, oxidative stress and inflammation. Cardamom also improved dyslipidemia, but had no substantial effect on weight loss.

Outcomes Measured

  • inflammatory markers

Population

Field Value
Population See abstract
Sample Size See abstract
Age Range See abstract
Condition stress

MeSH Terms

  • Animals
  • Humans
  • Elettaria
  • Diabetes Mellitus, Type 2
  • Dyslipidemias
  • Inflammation
  • Diabetes Complications

Evidence Classification

  • Level: Systematic Review
  • Publication Types: Systematic Review, Journal Article
  • Vertical: quercetin

Provenance

Source extracted via PubMed E-utilities API on 2026-04-09