Antimicrobial activity of cleansers on the cobalt-chromium surface of removable partial denture: a systematic review

source extracted confidence: high 2026-04-09
#humans #anti-infective-agents #chlorhexidine #chromium-alloys #cobalt

Antimicrobial activity of cleansers on the cobalt-chromium surface of removable partial denture: a systematic review

Freiria et al., 2023 | Biofouling | Systematic Review

Citation

Freiria de Oliveira Carolina Alves, Moraes Leonardo Guedes da Silva, ... Pagnano Valéria Oliveira. Antimicrobial activity of cleansers on the cobalt-chromium surface of removable partial denture: a systematic review. Biofouling. 2023;39(9-10):916-927. doi:10.1080/08927014.2023.2290120

Abstract

This study aimed to review systematically the literature about the antimicrobial action of evaluated cleansers on the Co-Cr alloy of RPD. The search was conducted in MEDLINE/PubMed, Scopus, Lilacs, Embase and Science Direct May, 2022. The review was performed based on PRISMA guidelines and recorded in Open Science Framework. Independent reviewers performed the search, selection, extraction, and analysis of the data. The risk of bias of the in vitro and clinical trials studies was analyzed by the Joanna Briggs Institute tool. A total of 187 articles were found and 9 were included. The cleansers that showed antimicrobial action were 2% and 5.25% sodium hypochlorite, 0.12% chlorhexidine and NitrAdine effervescent tablet. Polident, Corega Tabs effervescent tablets and 5 mg/mL chitosan solution showed intermediate effects. Propolis and green tea toothpaste were not effective. Three articles presented a high risk of bias and 6, low risk. The cleansers that showed the highest antimicrobial efficacy on Co-Cr alloy were 0.12% chlorhexidine digluconate and NitrAdine and can be safely used on RPD framework.

Key Findings

The cleansers that showed the highest antimicrobial efficacy on Co-Cr alloy were 0.12% chlorhexidine digluconate and NitrAdine and can be safely used on RPD framework.

Outcomes Measured

  • Requires manual extraction

Population

Field Value
Population See abstract
Sample Size See abstract
Age Range See abstract
Condition See abstract

MeSH Terms

  • Humans
  • Anti-Infective Agents
  • Chlorhexidine
  • Chromium Alloys
  • Cobalt
  • Denture Cleansers
  • Denture, Partial, Removable

Evidence Classification

  • Level: Systematic Review
  • Publication Types: Journal Article, Systematic Review
  • Vertical: chromium

Provenance

Source extracted via PubMed E-utilities API on 2026-04-09