Herbal Therapeutics for Alzheimer's Disease: Ancient Indian Medicine System from the Modern Viewpoint

source extracted confidence: high 2026-04-09
#humans #alzheimer-disease #neurodegenerative-diseases #quality-of-life #phytotherapy

Herbal Therapeutics for Alzheimer's Disease: Ancient Indian Medicine System from the Modern Viewpoint

Kushwah et al., 2023 | Curr Neuropharmacol | Systematic Review

Citation

Kushwah Shikha, Maurya Neha Shree, ... Mani Ashutosh. Herbal Therapeutics for Alzheimer's Disease: Ancient Indian Medicine System from the Modern Viewpoint. Curr Neuropharmacol. 2023;21(4):764-776. doi:10.2174/1570159X21666230216094353

Abstract

Alzheimer's is a chronic neurodegenerative disease where amyloid-beta (Aβ) plaques and neurofibrillary tangles are formed inside the brain. It is also characterized by progressive memory loss, depression, neuroinflammation, and derangement of other neurotransmitters. Due to its complex etiopathology, current drugs have failed to completely cure the disease. Natural compounds have been investigated as an alternative therapy for their ability to treat Alzheimer's disease (AD). Traditional herbs and formulations which are used in the Indian ayurvedic system are rich sources of antioxidant, anti-amyloidogenic, neuroprotective, and anti-inflammatory compounds. They promote quality of life by improving cognitive memory and rejuvenating brain functioning through neurogenesis. A rich knowledge base of traditional herbal plants (Turmeric, Gingko, Ashwagandha, Shankhpushpi, Giloy, Gotu kola, Garlic, Tulsi, Ginger, and Cinnamon) combined with modern science could suggest new functional leads for Alzheimer's drug discovery. In this article Ayurveda, the ancient Indian herbal medicine system based on multiple clinical and experimental, evidence have been reviewed for treating AD and improving brain functioning. This article presents a modern perspective on the herbs available in the ancient Indian medicine system as well as their possible mechanisms of action for AD treatment. The main objective of this research is to provide a systematic review of herbal drugs that are easily accessible and effective for the treatment of AD.

Key Findings

The main objective of this research is to provide a systematic review of herbal drugs that are easily accessible and effective for the treatment of AD.

Outcomes Measured

  • depression
  • inflammatory markers

Population

Field Value
Population See abstract
Sample Size See abstract
Age Range See abstract
Condition depression

MeSH Terms

  • Humans
  • Alzheimer Disease
  • Neurodegenerative Diseases
  • Quality of Life
  • Phytotherapy
  • Plant Extracts
  • Ocimum sanctum

Evidence Classification

  • Level: Systematic Review
  • Publication Types: Systematic Review, Journal Article
  • Vertical: ashwagandha

Provenance

Source extracted via PubMed E-utilities API on 2026-04-09