Curcumin and blood lipid levels: an updated systematic review and meta-analysis of randomised clinical trials

Saeedi et al., 2022 | Arch Physiol Biochem | Meta Analysis

Citation

Saeedi Farhad, Farkhondeh Tahereh, ... Samarghandian Saeed. Curcumin and blood lipid levels: an updated systematic review and meta-analysis of randomised clinical trials. Arch Physiol Biochem. 2022-Dec;128(6):1493-1502. doi:10.1080/13813455.2020.1779309

Abstract

The present study was designed to indicate the protective effects of curcumin on dyslipidemia. Main databases were searched to recognise randomised clinical trials evaluating the effect of curcumin on blood lipid profiles. The pooled odds ratio with a 95% confidence interval (CI) was used to evaluate the effect of curcumin on blood lipid parameters. HDL-C levels in the curcumin group were 0.04-fold lower than placebo (95% CI:-0.36-0.29; Z = 0.23; p = .82). LDL-C levels in the curcumin group reduced by 0.17 versus the placebo group (95% CI: -0.43-0.09; Z = 1.27; p = .2). TC levels in the curcumin group were 0.21 lower versus the placebo group (95% CI: -0.55-0.13; Z = 1.22; p = .22). TG level in the curcumin group were 0.05 lower versus the placebo (95% CI: -0.20-0.11; Z = 0.58; p = .56). This study suggests that curcumin may reduce blood lipid levels and can be used as a hypolipidemic agent.

Key Findings

This study suggests that curcumin may reduce blood lipid levels and can be used as a hypolipidemic agent.

Outcomes Measured

• Requires manual extraction

Population

MeSH Terms

• Humans
• Curcumin
• Cholesterol, LDL
• Lipids
• Dyslipidemias
• Hypolipidemic Agents
• Triglycerides
• Randomized Controlled Trials as Topic

Evidence Classification

• Level: Meta Analysis
• Publication Types: Meta-Analysis, Systematic Review, Journal Article
• Vertical: curcumin

Provenance

• PMID: 36264280
• DOI: 10.1080/13813455.2020.1779309
• PMCID: Not in PMC
• Verified: 2026-04-09 via PubMed E-utilities API

Source extracted via PubMed E-utilities API on 2026-04-09