The Effects of Quercetin Supplementation on Blood Pressure - Meta-Analysis

Popiolek-Kalisz et al., 2022 | Curr Probl Cardiol | Meta Analysis

Citation

Popiolek-Kalisz Joanna, Fornal Emilia. The Effects of Quercetin Supplementation on Blood Pressure - Meta-Analysis. Curr Probl Cardiol. 2022-Nov;47(11):101350. doi:10.1016/j.cpcardiol.2022.101350

Abstract

The effects of quercetin supplementation on blood pressure (BP) remain unclear. The aim of this meta-analysis is to summarize data focused on quercetin impact on systolic BP (SBP) and diastolic BP (DBP). Medline, EMBASE and Web of Science databases were searched to identify randomized controlled trials that assessed the impact of quercetin on BP until May 2022. A random-effects model was used for data analysis. Subgroup analysis was performed to explore the effects in (pre)hypertensive and normotensive adults. Ten trials (841 participants in total) were included into the analysis. The results showed that quercetin supplementation significantly decreased SBP in the mixed population (MD: -2.38mmHg; 95% CI: -3.80 - -0.96; P = 0.01) and in the normotensive subgroup (MD: -1.82mmHg; 95% CI: -2.43 - -1.20; P < 0.0001) and DBP in the (pre)hypertensive subgroup (MD: -3.14mmHg; 95% CI: -4.44 - -1.84; P < 0.00001). Quercetin supplementation decreases BP in normotensive and (pre)hypertensive patients.

Key Findings

Quercetin supplementation decreases BP in normotensive and (pre)hypertensive patients.

Outcomes Measured

• blood pressure
• systolic blood pressure
• diastolic blood pressure

Population

MeSH Terms

• Adult
• Blood Pressure
• Dietary Supplements
• Humans
• Hypertension
• Quercetin

Evidence Classification

• Level: Meta Analysis
• Publication Types: Journal Article, Meta-Analysis, Review
• Vertical: quercetin

Provenance

• PMID: 35948195
• DOI: 10.1016/j.cpcardiol.2022.101350
• PMCID: Not in PMC
• Verified: 2026-04-09 via PubMed E-utilities API

Source extracted via PubMed E-utilities API on 2026-04-09