Tea consumption and cerebral hemorrhage risk: a meta-analysis

source extracted confidence: high 2026-04-09
#adult #cerebral-hemorrhage #humans #odds-ratio #polyphenols

Tea consumption and cerebral hemorrhage risk: a meta-analysis

Cheng et al., 2022 | Acta Neurol Belg | Meta Analysis

Citation

Cheng Pengfei, Zhang Junxiang, ... Zhu Jiaying. Tea consumption and cerebral hemorrhage risk: a meta-analysis. Acta Neurol Belg. 2022-Oct;122(5):1247-1259. doi:10.1007/s13760-022-01973-6

Abstract

BACKGROUND: Tea contains many polyphenols with biological properties such as antithrombosis and antioxidation. Recent observational studies on tea consumption concerning cerebral hemorrhage risk have reported inconsistent results. This meta-analysis aimed to summarize the accumulated evidence on the association between tea consumption and cerebral hemorrhage risk. METHODS: Web of Science, PubMed, Embase, and Scopus databases were searched to identify relevant studies through December 2021. Relative risks (RRs) or odds ratios (ORs) from observational studies were synthesized. RESULTS: Ten studies involving over 721,827 participants were included. Higher tea consumption was correlated with a 23% (RR = 0.77; 95% CI 0.66-0.89) lower risk of cerebral hemorrhage. Subgroup meta-analyses indicated higher tea consumption was beneficial in preventing cerebral hemorrhage risk for green tea, alcohol-adjusted, fruit/vegetables-adjusted, and physical activity-adjusted subgroups, respectively (P < 0.01). Dose-response analysis indicated each one-cup (120 ml/cup) increment in tea or green tea intake/day was correlated with an average of 2% (RR = 0.98, 95% CI 0.976-0.990), or 6% (RR = 0.94; 95% CI 0.92-0.97) lower cerebral hemorrhage risk. CONCLUSIONS: This study suggests that daily tea consumption is related to a lower risk of cerebral hemorrhage among adults. Green tea consumption appears to be more beneficial in preventing cerebral hemorrhage. Physical activity, fruit/vegetables, and alcohol may affect the relationship between tea consumption and hemorrhagic stroke. Future studies should investigate the interplay of tea with these factors.

Key Findings

Ten studies involving over 721,827 participants were included. Higher tea consumption was correlated with a 23% (RR = 0.77; 95% CI 0.66-0.89) lower risk of cerebral hemorrhage. Subgroup meta-analyses indicated higher tea consumption was beneficial in preventing cerebral hemorrhage risk for green tea, alcohol-adjusted, fruit/vegetables-adjusted, and physical activity-adjusted subgroups, respectively (P < 0.01). Dose-response analysis indicated each one-cup (120 ml/cup) increment in tea or green t

Outcomes Measured

  • Requires manual extraction

Population

Field Value
Population See abstract
Sample Size 721827
Age Range See abstract
Condition See abstract

MeSH Terms

  • Adult
  • Cerebral Hemorrhage
  • Humans
  • Odds Ratio
  • Polyphenols
  • Risk Factors
  • Tea
  • Vegetables

Evidence Classification

  • Level: Meta Analysis
  • Publication Types: Journal Article, Meta-Analysis
  • Vertical: green-tea

Provenance

Source extracted via PubMed E-utilities API on 2026-04-09