Association between health risk factors and dietary flavonoid intake in cohort studies

source extracted confidence: high 2026-04-09
#cardiovascular-diseases #diet #flavonoids #humans #polyphenols

Association between health risk factors and dietary flavonoid intake in cohort studies

Micek et al., 2021 | Int J Food Sci Nutr | Meta Analysis

Citation

Micek Agnieszka, Raźny Urszula, Paweł Kawalec. Association between health risk factors and dietary flavonoid intake in cohort studies. Int J Food Sci Nutr. 2021-Dec;72(8):1019-1034. doi:10.1080/09637486.2021.1908965

Abstract

The aim of this study was to identify the health risk factors associated with flavonoid intake in cohort studies investigating the association between dietary polyphenols and the risk of cardiovascular disease (CVD). A systematic search of the PubMed and EMBASE databases was performed. Prospective studies with the background characteristics given for categories of flavonoid intake were eligible to inclusion. A bivariate meta-analysis summarising the intercepts and slopes of the linear regression and a dose-response meta-analysis of differences in means were used to analyse the relationships. The intake of total flavonoids was inversely associated with BMI, alcohol consumption, saturated fat intake, and current smoking, and positively associated with vitamin E, folate, fibre, beta-carotene intake, multivitamin supplement use, and high physical activity. The results of this study underline the importance of considering the association between dietary flavonoid consumption and CVD risk in the context of a healthy lifestyle.

Key Findings

The results of this study underline the importance of considering the association between dietary flavonoid consumption and CVD risk in the context of a healthy lifestyle.

Outcomes Measured

  • Requires manual extraction

Population

Field Value
Population See abstract
Sample Size See abstract
Age Range See abstract
Condition See abstract

MeSH Terms

  • Cardiovascular Diseases
  • Diet
  • Flavonoids
  • Humans
  • Polyphenols
  • Prospective Studies
  • Risk Factors

Evidence Classification

  • Level: Meta Analysis
  • Publication Types: Journal Article, Meta-Analysis, Systematic Review
  • Vertical: vitamin-e

Provenance

Source extracted via PubMed E-utilities API on 2026-04-09