Advances in Research on the Toxicological Effects of Selenium

source extracted confidence: high 2026-04-09
#dietary-supplements #metals-heavy #micronutrients #pharmaceutical-preparations #selenium

Advances in Research on the Toxicological Effects of Selenium

Lv et al., 2021 | Bull Environ Contam Toxicol | Systematic Review

Citation

Lv Qizhuang, Liang Xiaomei, ... Zhu Yulin. Advances in Research on the Toxicological Effects of Selenium. Bull Environ Contam Toxicol. 2021-May;106(5):715-726. doi:10.1007/s00128-020-03094-3

Abstract

Selenium is a trace element necessary for the growth of organisms. Moreover, selenium supplementation can improve the immunity and fertility of the body, as well as its ability to resist oxidation, tumors, heavy metals, and pathogenic microorganisms. However, owing to the duality of selenium, excessive selenium supplementation can cause certain toxic effects on the growth and development of the body and may even result in death in severe cases. At present, increasing attention is being paid to the development and utilization of selenium as a micronutrient, but its potential toxicity tends to be neglected. This study systematically reviews recent research on the toxicological effects of selenium, aiming to provide theoretical references for selenium toxicology-related research and theoretical support for the development of selenium-containing drugs, selenium-enriched dietary supplements, and selenium-enriched foods.

Key Findings

This study systematically reviews recent research on the toxicological effects of selenium, aiming to provide theoretical references for selenium toxicology-related research and theoretical support for the development of selenium-containing drugs, selenium-enriched dietary supplements, and selenium-enriched foods.

Outcomes Measured

  • Requires manual extraction

Population

Field Value
Population See abstract
Sample Size See abstract
Age Range See abstract
Condition See abstract

MeSH Terms

  • Dietary Supplements
  • Metals, Heavy
  • Micronutrients
  • Pharmaceutical Preparations
  • Selenium
  • Trace Elements

Evidence Classification

  • Level: Systematic Review
  • Publication Types: Journal Article, Systematic Review
  • Vertical: selenium

Provenance

Source extracted via PubMed E-utilities API on 2026-04-09