Effects of Creatine Supplementation during Resistance Training Sessions in Physically Active Young Adults

source extracted confidence: high 2026-04-09
#adult #creatine #dietary-supplements #double-blind-method #exercise

Effects of Creatine Supplementation during Resistance Training Sessions in Physically Active Young Adults

Mills et al., 2020 | Nutrients | Rct

Citation

Mills Scotty, Candow Darren G, ... Antonio Jose. Effects of Creatine Supplementation during Resistance Training Sessions in Physically Active Young Adults. Nutrients. 2020-Jun-24;12(6). doi:10.3390/nu12061880

Abstract

The purpose was to examine the effects of creatine supplementation during resistance training sessions on skeletal muscle mass and exercise performance in physically active young adults. Twenty-two participants were randomized to supplement with creatine (CR: n = 13, 26 ± 4 yrs; 0.0055 g·kg-1 post training set) or placebo (PLA: n = 9, 26 ± 5 yrs; 0.0055 g·kg-1 post training set) during six weeks of resistance training (18 sets per training session; five days per week). Prior to and following training and supplementation, measurements were made for muscle thickness (elbow and knee flexors/extensors, ankle plantarflexors), power (vertical jump and medicine ball throw), strength (leg press and chest press one-repetition maximum (1-RM)) and muscular endurance (one set of repetitions to volitional fatigue using 50% baseline 1-RM for leg press and chest press). The creatine group experienced a significant increase (p < 0.05) in leg press, chest press and total body strength and leg press endurance with no significant changes in the PLA group. Both groups improved total body endurance over time (p < 0.05), with greater gains observed in the creatine group. In conclusion, creatine ingestion during resistance training sessions is a viable strategy for improving muscle strength and some indices of muscle endurance in physically active young adults.

Key Findings

In conclusion, creatine ingestion during resistance training sessions is a viable strategy for improving muscle strength and some indices of muscle endurance in physically active young adults.

Outcomes Measured

  • Requires manual extraction

Population

Field Value
Population See abstract
Sample Size 13
Age Range See abstract
Condition See abstract

MeSH Terms

  • Adult
  • Creatine
  • Dietary Supplements
  • Double-Blind Method
  • Exercise
  • Female
  • Humans
  • Male
  • Muscle Strength
  • Muscle, Skeletal
  • Resistance Training
  • Young Adult

Evidence Classification

  • Level: Rct
  • Publication Types: Journal Article, Randomized Controlled Trial
  • Vertical: creatine-muscle

Provenance

Source extracted via PubMed E-utilities API on 2026-04-09