Efficacy and safety of ginkgo injections in the treatment of angina pectoris caused by coronary heart disease in China: a network Meta-analysis and systematic review

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#angina-pectoris #animals #coronary-disease #ginkgo-biloba #humans

Efficacy and safety of ginkgo injections in the treatment of angina pectoris caused by coronary heart disease in China: a network Meta-analysis and systematic review

Tan et al., 2019 | J Tradit Chin Med | Systematic Review

Citation

Tan Di, Wu Jiarui, ... Jing Zhiwei. Efficacy and safety of ginkgo injections in the treatment of angina pectoris caused by coronary heart disease in China: a network Meta-analysis and systematic review. J Tradit Chin Med. 2019-Jun;39(3):285-296

Abstract

OBJECTIVE: To assess the clinical efficacy and safety of ginkgo injections (GIs) combined with conventional treatment (CT) against angina pectoris (AP) due to coronary heart disease (CHD). METHODS: Randomized controlled trials (RCTs) that used GIs to treat AP were searched in SinoMed, PubMed, China National Knowledge Infrastructure Database, Chinese Scientific Journals Database, Wanfang Database, Embase and Cochrane Library until March 2017. The Cochrane"risk of bias"method was used to evaluate the methodological quality of RCTs. Data were analyzed using Stata v13.1 and WinBUGS v1.4.3. RESULTS: A total of 73 RCTs involving 7621 patients were included. A Bayesian network Meta-analysis of RCTs was undertaken, and the advantages of four types of GI-supplemented CT in AP treatment were determined. CONCLUSION: GI-assisted CT was more effective against AP than CT alone. However, based on the limitations of the study, additional high-quality RCTs are required to confirm our findings.

Key Findings

A total of 73 RCTs involving 7621 patients were included. A Bayesian network Meta-analysis of RCTs was undertaken, and the advantages of four types of GI-supplemented CT in AP treatment were determined.

Outcomes Measured

  • Requires manual extraction

Population

Field Value
Population See abstract
Sample Size 7621
Age Range See abstract
Condition See abstract

MeSH Terms

  • Angina Pectoris
  • Animals
  • Coronary Disease
  • Ginkgo biloba
  • Humans
  • Plant Extracts
  • Randomized Controlled Trials as Topic
  • Treatment Outcome
  • Ginkgo Extract

Evidence Classification

  • Level: Systematic Review
  • Publication Types: Journal Article, Research Support, Non-U.S. Gov't, Systematic Review, Network Meta-Analysis
  • Vertical: ginkgo

Provenance

  • PMID: 32186000
  • DOI: (not available)
  • PMCID: Not in PMC
  • Verified: 2026-04-09 via PubMed E-utilities API

Source extracted via PubMed E-utilities API on 2026-04-09