A dose-response meta-analysis of green tea consumption and breast cancer risk

Wang et al., 2020 | Int J Food Sci Nutr | Meta Analysis

Citation

Wang Yanli, Zhao Yanyan, ... Song Chunhua. A dose-response meta-analysis of green tea consumption and breast cancer risk. Int J Food Sci Nutr. 2020-Sep;71(6):656-667. doi:10.1080/09637486.2020.1715353

Abstract

Whether drinking green tea (GT) could reduce the risk of breast cancer (BC) is still controversial. The search was performed using PubMed, Embase and Web of Science databases. The generalised least square method and constrained cubic spline model were performed to assess the dose-response trends between GT consumption and BC risk. The attributable risk proportion (ARP) was also calculated. A total of 16 studies were included and the pooled relative risks was 0.86 (95%CI: 0.75-0.99) for BC risk at the highest vs. lowest levels of GT consumption. GT consumption (pnonlinearity = .110), drinking GT years (pnonlinearity = .393) and BC risk were both negatively linearly correlated. Moreover, The ARP results demonstrated in China, people who drink GT do not suffer from BC, 23.5% of which may be attributed to drinking GT. In conclusion, drinking GT may have a positive effect on reducing BC risk, especially in long-term, high doses.

Key Findings

In conclusion, drinking GT may have a positive effect on reducing BC risk, especially in long-term, high doses.

Outcomes Measured

Requires manual extraction

Population

Field	Value
Population	See abstract
Sample Size	16
Age Range	See abstract
Condition	See abstract

MeSH Terms

Adult
Beverages
Breast Neoplasms
Dose-Response Relationship, Drug
Female
Humans
Observational Studies as Topic
Postmenopause
Premenopause
Risk
Tea

Evidence Classification

Level: Meta Analysis
Publication Types: Journal Article, Meta-Analysis
Vertical: green-tea

Provenance

PMID: 31959020
DOI: 10.1080/09637486.2020.1715353
PMCID: Not in PMC
Verified: 2026-04-09 via PubMed E-utilities API

Source extracted via PubMed E-utilities API on 2026-04-09