The Effects of Psychological and Environmental Stress on Micronutrient Concentrations in the Body: A Review of the Evidence
The Effects of Psychological and Environmental Stress on Micronutrient Concentrations in the Body: A Review of the Evidence
Lopresti et al., 2020 | Adv Nutr | Systematic Review
Citation
Lopresti Adrian L. The Effects of Psychological and Environmental Stress on Micronutrient Concentrations in the Body: A Review of the Evidence. Adv Nutr. 2020-Jan-01;11(1):103-112. doi:10.1093/advances/nmz082
Abstract
Stress is the nonspecific response of the body to any demand for change. Excess or chronic psychological or environmental stress is associated with an increased risk of mental and physical diseases, with several mechanisms theorized to be associated with its detrimental effects. One underappreciated potential mechanism relates to the effects of psychological and environmental stress on micronutrient concentrations. Micronutrients (vitamins and minerals) are essential for optimal physical and mental function, with deficiencies associated with an array of diseases. In this article, animal and human studies investigating the effects of various psychological and environmental stressors on micronutrient concentrations are reviewed. In particular, the effects of psychological stress, sleep deprivation, and physical exercise on micronutrient concentrations and micronutrient excretion are summarized. Micronutrients identified in this review include magnesium, zinc, calcium, iron, and niacin. Overall, the bulk of evidence suggests stress can affect micronutrient concentrations, often leading to micronutrient depletion. However, before definitive conclusions about the effects of stress can be made, the impact of different stressors, stress severity, and acute versus chronic stress on micronutrient concentrations requires investigation. Moreover, the impact of stress on micronutrients in different populations varying in age, gender, and premorbid health status and the durability of changes after a stressor is resolved require examination. The medical, physical, and psychological implications of nutrient changes caused by a stressor also remain to be determined.
Key Findings
The medical, physical, and psychological implications of nutrient changes caused by a stressor also remain to be determined.
Outcomes Measured
- Requires manual extraction
Population
| Field | Value |
|---|---|
| Population | See abstract |
| Sample Size | See abstract |
| Age Range | See abstract |
| Condition | sleep |
MeSH Terms
- Animals
- Deficiency Diseases
- Environment
- Female
- Humans
- Iron
- Magnesium
- Male
- Micronutrients
- Niacin
- Nutritional Status
- Stress, Physiological
- Stress, Psychological
- Zinc
Evidence Classification
- Level: Systematic Review
- Publication Types: Journal Article, Systematic Review
- Vertical: niacin
Provenance
- PMID: 31504084
- DOI: 10.1093/advances/nmz082
- PMCID: PMC7442351
- Verified: 2026-04-09 via PubMed E-utilities API
Source extracted via PubMed E-utilities API on 2026-04-09