Green tea as a safe alternative approach for nonalcoholic fatty liver treatment: A systematic review and meta-analysis of clinical trials

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#alanine-transaminase #aspartate-aminotransferases #body-mass-index #cholesterol-hdl #cholesterol-ldl

Green tea as a safe alternative approach for nonalcoholic fatty liver treatment: A systematic review and meta-analysis of clinical trials

Mansour-Ghanaei et al., 2018 | Phytother Res | Meta Analysis

Citation

Mansour-Ghanaei Fariborz, Hadi Amir, ... Najafgholizadeh Ameneh. Green tea as a safe alternative approach for nonalcoholic fatty liver treatment: A systematic review and meta-analysis of clinical trials. Phytother Res. 2018-Oct;32(10):1876-1884. doi:10.1002/ptr.6130

Abstract

This study aimed to evaluate the efficacy of green tea supplementation on nonalcoholic fatty liver disease treatment. Electronic databases, including PubMed, Scopus, Web of Science, and Google Scholar, were systematically searched up to October 30, 2017, to identify eligible trials based on the inclusion criteria. The effect size was presented as mean difference with 95% confidence intervals (CI). The meta-analysis of data from four studies indicated significant effects of green tea supplementation in altering alanine aminotransferases (-12.81 U/L; 95% CI: -18.17 to -7.45) and aspartate aminotransferases (-10.91 U/L; 95% CI: -19.66 to -2.17) blood concentrations. Likewise, a favorable effect of green tea administration was observed on body mass index (-2.08 kg/cm2 ; 95% CI: -2.81 to -1.36), triacylglycerol (-31.87 mg/dl; 95% CI: -40.62 to -23.12), total cholesterol (-27.57 mg/dl; 95% CI: -36.17 to -18.98), and low-density lipoprotein cholesterol (-14.15 mg/dl; 95% CI: -23.69 to -4.60), whereas no significant effect was detected on high-density lipoprotein cholesterol concentrations (7.41 mg/dl; 95% CI: -1.49 to 16.30) and homeostasis model assessment of insulin resistance (-4.06; 95% CI: -10.22 to 2.09). This systematic review and meta-analysis of available trials suggests that there  are potential benefits of green tea supplementation on nonalcoholic fatty liver disease.

Key Findings

This systematic review and meta-analysis of available trials suggests that there  are potential benefits of green tea supplementation on nonalcoholic fatty liver disease.

Outcomes Measured

  • Requires manual extraction

Population

Field Value
Population See abstract
Sample Size See abstract
Age Range See abstract
Condition See abstract

MeSH Terms

  • Alanine Transaminase
  • Aspartate Aminotransferases
  • Body Mass Index
  • Cholesterol, HDL
  • Cholesterol, LDL
  • Humans
  • Insulin Resistance
  • Non-alcoholic Fatty Liver Disease
  • Plant Extracts
  • Randomized Controlled Trials as Topic
  • Tea
  • Triglycerides

Evidence Classification

  • Level: Meta Analysis
  • Publication Types: Journal Article, Meta-Analysis, Systematic Review
  • Vertical: green-tea

Provenance

Source extracted via PubMed E-utilities API on 2026-04-09