[Studies on chemical constituents of Valeriana plants and their biological activities]

Wang et al., 2016 | Zhongguo Zhong Yao Za Zhi | Systematic Review

Citation

Wang Ru-Jing, Huang Qing, ... Zhang Hai. [Studies on chemical constituents of Valeriana plants and their biological activities]. Zhongguo Zhong Yao Za Zhi. 2016-Apr;41(8):1405-1414. doi:10.4268/cjcmm20160807

Abstract

The recent progresses on chemical components and pharmacological activities of the genus Valerianawere summarized.Besides-essential oil, the chemical composition of Valerianais mainly focused on monoterpenoids,sesquiterpenoids,lignans, flavonoids, alkaloids, etc. Iridoids are the main chemical components ofmonoterpenoids. There are two types ofiridoidson the basis of the cyclopentane open or not. The Valerianahas been drawmuch attention for their significant sedation,spasmolysis,antidepression,antitumor, against adenosine A1 receptors and cytotoxicityactivity,and had certain function for cardiovascular disease treatment. Given to the fact of the lack of systematic review and summary of studies on the Valeriana, we summarized and analyze the study literatures on the pharmacological activity of Valerianain recent years, and providedsome basisfor further study.

Key Findings

Given to the fact of the lack of systematic review and summary of studies on the Valeriana, we summarized and analyze the study literatures on the pharmacological activity of Valerianain recent years, and providedsome basisfor further study.

Outcomes Measured

depression

Population

Field	Value
Population	See abstract
Sample Size	See abstract
Age Range	See abstract
Condition	depression

MeSH Terms

Drugs, Chinese Herbal
Humans
Iridoids
Valerian

Evidence Classification

Level: Systematic Review
Publication Types: Journal Article, Systematic Review
Vertical: valerian

Provenance

PMID: 28884531
DOI: 10.4268/cjcmm20160807
PMCID: Not in PMC
Verified: 2026-04-09 via PubMed E-utilities API

Source extracted via PubMed E-utilities API on 2026-04-09