Coenzyme Q10 in breast cancer care

source extracted confidence: high 2026-04-09
#animals #antineoplastic-agents #antioxidants #breast-neoplasms #clinical-trials-as-topic

Coenzyme Q10 in breast cancer care

Tafazoli et al., 2017 | Future Oncol | Meta Analysis

Citation

Tafazoli Ali. Coenzyme Q10 in breast cancer care. Future Oncol. 2017-May;13(11):1035-1041. doi:10.2217/fon-2016-0547

Abstract

INTRODUCTION: Breast cancer (BC) is the most common type of cancers with high rates of morbidity and mortality. By now numerous medical approaches are available for treatment of BC including chemotherapies, radiation and surgery. These are accompanied by several complications like partial effectiveness, fatal adverse effects and high cost. Numerous studies in recent years tried to find safe and effective alternatives. A promising candidate is coenzyme Q10 which is an antioxidant that can target the mechanisms of BC tumor progression. METHODS & RESULTS: In this systematic review via PubMed searching, sparse but promising findings were classified about the successful application of this compound as an adjunct in prevention and treatment of BC and its comorbidities with some contradicting data about its null effect. DISCUSSION & CONCLUSION: According to the results, further well-designed clinical studies with dose optimization are now required to stratify the role of this supplement in current BC regimens.

Key Findings

In this systematic review via PubMed searching, sparse but promising findings were classified about the successful application of this compound as an adjunct in prevention and treatment of BC and its comorbidities with some contradicting data about its null effect. DISCUSSION & CONCLUSION: According to the results, further well-designed clinical studies with dose optimization are now required to stratify the role of this supplement in current BC regimens.

Outcomes Measured

  • Requires manual extraction

Population

Field Value
Population See abstract
Sample Size See abstract
Age Range See abstract
Condition See abstract

MeSH Terms

  • Animals
  • Antineoplastic Agents
  • Antioxidants
  • Breast Neoplasms
  • Clinical Trials as Topic
  • Disease Management
  • Drug Evaluation, Preclinical
  • Female
  • Humans
  • Treatment Outcome
  • Ubiquinone

Evidence Classification

  • Level: Meta Analysis
  • Publication Types: Journal Article, Meta-Analysis, Systematic Review
  • Vertical: coq10

Provenance

Source extracted via PubMed E-utilities API on 2026-04-09