Prenatal DHA supplementation and infant attention

source extracted confidence: high 2026-04-09
#adult #attention #cognition #dietary-supplements #docosahexaenoic-acids

Prenatal DHA supplementation and infant attention

Colombo et al., 2016 | Pediatr Res | Rct

Citation

Colombo John, Gustafson Kathleen M, ... Carlson Susan E. Prenatal DHA supplementation and infant attention. Pediatr Res. 2016-Nov;80(5):656-662. doi:10.1038/pr.2016.134

Abstract

BACKGROUND: Results of randomized trials on the effects of prenatal docosahexaenoic acid (DHA) on infant cognition are mixed, but most trials have used global standardized outcomes, which may not be sensitive to effects of DHA on specific cognitive domains. METHODS: Women were randomized to 600 mg/d DHA or a placebo for the last two trimesters of pregnancy. Infants of these mothers were then followed on tests of visual habituation at 4, 6, and 9 mo of age. RESULTS: DHA supplementation did not affect look duration or habituation parameters but infants of supplemented mothers maintained high levels of sustained attention (SA) across the first year; SA declined for the placebo group. The supplemented group also showed significantly reduced attrition on habituation tasks, especially at 6 and 9 mo. CONCLUSION: The findings support with the suggestion that prenatal DHA may positively affect infants' attention and regulation of state.

Key Findings

DHA supplementation did not affect look duration or habituation parameters but infants of supplemented mothers maintained high levels of sustained attention (SA) across the first year; SA declined for the placebo group. The supplemented group also showed significantly reduced attrition on habituation tasks, especially at 6 and 9 mo.

Outcomes Measured

  • Requires manual extraction

Population

Field Value
Population See abstract
Sample Size See abstract
Age Range See abstract
Condition cognitive

MeSH Terms

  • Adult
  • Attention
  • Cognition
  • Dietary Supplements
  • Docosahexaenoic Acids
  • Female
  • Follow-Up Studies
  • Heart Rate
  • Humans
  • Infant
  • Infant, Newborn
  • Male
  • Maternal Nutritional Physiological Phenomena
  • Pregnancy
  • Pregnancy Trimester, Second
  • Pregnancy Trimester, Third
  • Time Factors
  • Treatment Outcome

Evidence Classification

  • Level: Rct
  • Publication Types: Journal Article, Randomized Controlled Trial, Research Support, N.I.H., Extramural
  • Vertical: omega-3-adhd

Provenance

Source extracted via PubMed E-utilities API on 2026-04-09