Association Between Antioxidant Intake/Status and Obesity: a Systematic Review of Observational Studies
Association Between Antioxidant Intake/Status and Obesity: a Systematic Review of Observational Studies
Hosseini et al., 2017 | Biol Trace Elem Res | Systematic Review
Citation
Hosseini Banafshe, Saedisomeolia Ahmad, Allman-Farinelli Margaret. Association Between Antioxidant Intake/Status and Obesity: a Systematic Review of Observational Studies. Biol Trace Elem Res. 2017-Feb;175(2):287-297. doi:10.1007/s12011-016-0785-1
Abstract
The global prevalence of obesity has doubled in recent decades. Compelling evidences indicated that obesity was associated with lower concentrations of specific antioxidants which may play a role in the development of obesity-related diseases such as cardiovascular disease. The present review aimed to synthesize the evidence from studies on the association between obesity and antioxidant micronutrients in a systematic manner. Data bases including MEDLINE, Science Direct, and Cochrane were searched from inception to October 2015. Thirty-one articles were reviewed using the MOOSE checklist. Lower concentrations of antioxidants have been reported in obese individuals among age groups worldwide. Circulatory levels of carotenoids, vitamins E and C, as well as zinc, magnesium, and selenium were inversely correlated with obesity and body fat mass. However, studies demonstrated inconsistencies in findings. Lower status of carotenoids, vitamins E and C, zinc, magnesium, and selenium appears to be associated with adiposity. Intervention studies may be needed to establish the causality of these associations.
Key Findings
Intervention studies may be needed to establish the causality of these associations.
Outcomes Measured
- Requires manual extraction
Population
| Field | Value |
|---|---|
| Population | See abstract |
| Sample Size | See abstract |
| Age Range | See abstract |
| Condition | See abstract |
MeSH Terms
- Adiposity
- Antioxidants
- Cardiovascular Diseases
- Female
- Humans
- Male
- Micronutrients
- Obesity
- Observational Studies as Topic
Evidence Classification
- Level: Systematic Review
- Publication Types: Journal Article, Systematic Review
- Vertical: vitamin-c
Provenance
- PMID: 27334437
- DOI: 10.1007/s12011-016-0785-1
- PMCID: Not in PMC
- Verified: 2026-04-09 via PubMed E-utilities API
Source extracted via PubMed E-utilities API on 2026-04-09