Effectiveness of Aloe Vera gel compared with 1% silver sulphadiazine cream as burn wound dressing in second degree burns

Shahzad et al., 2013 | J Pak Med Assoc | Rct

Citation

Shahzad Muhammad Naveed, Ahmed Naheed. Effectiveness of Aloe Vera gel compared with 1% silver sulphadiazine cream as burn wound dressing in second degree burns. J Pak Med Assoc. 2013-Feb;63(2):225-30

Abstract

OBJECTIVE: To assess the efficacy of Aloe Vera gel compared with 1% silver sulfadiazine cream as a burn dressing for the treatment of superficial and partial thickness burns. METHODS: This Interventional Comparative study was carried out at the Burn unit and Plastic surgery department, Nishtar Hospital Multan, Pakistan from July 2008 to December 2010. A total of 50 patients with superficial and partial thickness burns were divided into two equal groups randomly by consecutive sampling method, one group was dressed with Aloe Vera gel while the other was treated with 1% silversulphadiazine cream, and the results regarding duration of wound epithelialization, pain relief and cost of treatment were compared. RESULTS: In patients treated with Aloe Vera gel, healing of burn wounds were remarkably early than those patients treated with 1% silver sulfadiazine. All the patients of Aloe Vera group were relieved of pain earlier than those patients who were treated with SSD. CONCLUSION: Thermal burns patients dressed with Aloe Vera gel showed advantage compared to those dressed with SSD regarding early wound epithelialization, earlier pain relief and cost-effectiveness.

Key Findings

In patients treated with Aloe Vera gel, healing of burn wounds were remarkably early than those patients treated with 1% silver sulfadiazine. All the patients of Aloe Vera group were relieved of pain earlier than those patients who were treated with SSD.

Outcomes Measured

  • Requires manual extraction

Population

Field Value
Population superficial and partial thickness
Sample Size 50
Age Range See abstract
Condition See abstract

MeSH Terms

  • Adolescent
  • Adult
  • Aged
  • Aloe
  • Anti-Infective Agents, Local
  • Bandages, Hydrocolloid
  • Burns
  • Child
  • Drug Combinations
  • Female
  • Humans
  • Male
  • Middle Aged
  • Pain
  • Silver Sulfadiazine
  • Time Factors
  • Wound Healing
  • Young Adult

Evidence Classification

  • Level: Rct
  • Publication Types: Comparative Study, Journal Article, Randomized Controlled Trial
  • Vertical: aloe-vera

Provenance

  • PMID: 23894900
  • DOI: (not available)
  • PMCID: Not in PMC
  • Verified: 2026-04-09 via PubMed E-utilities API

Source extracted via PubMed E-utilities API on 2026-04-09