Noni juice improves serum lipid profiles and other risk markers in cigarette smokers

source extracted confidence: high 2026-04-09
#adult #antioxidants #beverages #c-reactive-protein #cholesterol

Noni juice improves serum lipid profiles and other risk markers in cigarette smokers

Wang et al., 2012 | ScientificWorldJournal | Rct

Citation

Wang Mian-Ying, Peng Lin, ... West Brett J. Noni juice improves serum lipid profiles and other risk markers in cigarette smokers. ScientificWorldJournal. 2012;2012:594657. doi:10.1100/2012/594657

Abstract

Cigarette smoke-induced oxidative stress leads to dyslipidemia and systemic inflammation. Morinda citrifolia (noni) fruit juice has been found previously to have a significant antioxidant activity. One hundred thirty-two adult heavy smokers completed a randomized, double blind, placebo-controlled clinical trial designed to investigate the effect of noni juice on serum cholesterol, triglyceride, low density lipoprotein cholesterol (LDL), high density lipoprotein cholesterol (HDL), high-sensitivity C-reactive protein (hs-CRP), and homocysteine. Volunteers drank noni juice or a fruit juice placebo daily for one month. Drinking 29.5 mL to 188 mL of noni juice per day significantly reduced cholesterol levels, triglycerides, and hs-CRP. Decreases in LDL and homocysteine, as well increases in HDL, were also observed among noni juice drinkers. The placebo, which was devoid of iridoid glycosides, did not significantly influence blood lipid profiles or hs-CRP. Noni juice was able to mitigate cigarette smoke-induced dyslipidemia, an activity associated with the presence of iridoids.

Key Findings

Noni juice was able to mitigate cigarette smoke-induced dyslipidemia, an activity associated with the presence of iridoids.

Outcomes Measured

  • C-reactive protein

Population

Field Value
Population See abstract
Sample Size See abstract
Age Range See abstract
Condition stress

MeSH Terms

  • Adult
  • Antioxidants
  • Beverages
  • C-Reactive Protein
  • Cholesterol
  • Cholesterol, HDL
  • Cholesterol, LDL
  • Double-Blind Method
  • Dyslipidemias
  • Female
  • Homocysteine
  • Humans
  • Lipids
  • Male
  • Morinda
  • Oxidative Stress
  • Phytotherapy
  • Plant Extracts
  • Risk Factors
  • Smoking
  • Smoking Prevention
  • Triglycerides

Evidence Classification

  • Level: Rct
  • Publication Types: Journal Article, Randomized Controlled Trial, Research Support, Non-U.S. Gov't
  • Vertical: noni

Provenance

Source extracted via PubMed E-utilities API on 2026-04-12